. "Rauchov\u00E1, Hana" . "Physiological Research" . . . "Age-dependent salt hypertension in Dahl rats: fifty years of research"@en . "RIV/67985823:_____/12:00380467" . . . "CZ - \u010Cesk\u00E1 republika" . "Kadlecov\u00E1, Michaela" . . . . . . "Age-dependent salt hypertension in Dahl rats: fifty years of research" . "Kune\u0161, Jaroslav" . "I, P(1M0510), P(GA305/09/0336), P(GAP304/12/0259), Z(AV0Z50110509)" . . . . . "Age-dependent salt hypertension in Dahl rats: fifty years of research" . "000307133700005" . . . "9"^^ . "RIV/67985823:_____/12:00380467!RIV13-GA0-67985823" . . . "61" . . "9"^^ . "Suppl.1" . . "Age-dependent salt hypertension in Dahl rats: fifty years of research"@en . "54"^^ . . "Dobe\u0161ov\u00E1, Zdenka" . "[15C8B6A47A2E]" . "Vokurkov\u00E1, Martina" . . "121306" . "Hojn\u00E1, Silvie" . "0862-8408" . "Behuliak, Michal" . . "Zicha, Josef" . "We also searched for the age-dependent impact of environmental and pharmacological interventions, which modify the development of high blood pressure and/or organ damage, if they influence the salt-sensitive organism in particular critical periods of development (developmental windows). Thus, severe self-sustaining salt hypertension in young Dahl rats is characterized by pronounced dysbalance between augmented sympathetic hyperactivity and relative nitric oxide deficiency, attenuated baroreflex as well as by a major increase of residual blood pressure indicating profound remodeling of resistance vessels. Salt hypertension development in young but not in adult Dahl rats can be attenuated by preventive increase of potassium or calcium intake. On the contrary, moderate salt hypertension in adult Dahl rats is attenuated by superoxide scavenging or endothelin-A receptor blockade which do not affect salt hypertension development in young animals" . . . . "Behuliak, Michal" . . . . . "We also searched for the age-dependent impact of environmental and pharmacological interventions, which modify the development of high blood pressure and/or organ damage, if they influence the salt-sensitive organism in particular critical periods of development (developmental windows). Thus, severe self-sustaining salt hypertension in young Dahl rats is characterized by pronounced dysbalance between augmented sympathetic hyperactivity and relative nitric oxide deficiency, attenuated baroreflex as well as by a major increase of residual blood pressure indicating profound remodeling of resistance vessels. Salt hypertension development in young but not in adult Dahl rats can be attenuated by preventive increase of potassium or calcium intake. On the contrary, moderate salt hypertension in adult Dahl rats is attenuated by superoxide scavenging or endothelin-A receptor blockade which do not affect salt hypertension development in young animals"@en . "Van\u011B\u010Dkov\u00E1, Ivana" . "blood pressure; cell membrane transport; hemodynamics; vasoactive systems; cell calcium handling"@en .