. . "Flo11p, drug efflux pumps, and the extracellular matrix cooperate to form biofilm yeast colonies"@en . . . "P(GA204/08/0718), P(LC06063), P(LC531), Z(AV0Z50110509), Z(AV0Z50200510), Z(MSM0021620858)" . "5" . . "Flo11p, drug efflux pumps, and the extracellular matrix cooperate to form biofilm yeast colonies"@en . . "7"^^ . "Flo11p, drug efflux pumps, and the extracellular matrix cooperate to form biofilm yeast colonies" . . . "Hlav\u00E1\u010Dek, Otakar" . . "Kub\u00EDnov\u00E1, Lucie" . "Flo11p, drug efflux pumps, and the extracellular matrix cooperate to form biofilm yeast colonies" . "Palkov\u00E1, Z." . "RIV/67985823:_____/11:00369728!RIV12-AV0-67985823" . "10.1083/jcb.201103129" . . "Chernyavskiy, Oleksandr" . "US - Spojen\u00E9 st\u00E1ty americk\u00E9" . . "199997" . . "RIV/67985823:_____/11:00369728" . "CANDIDA-ALBICANS BIOFILMS; SACCHAROMYCES-CEREVISIAE; ABC TRANSPORTERS"@en . . . "9"^^ . "\u0160t\u011Bp\u00E1nek, L." . . "2"^^ . "The molecular mechanisms underlying the spatiotemporal development and environmental resistance of biofilms and colonies remain largely unknown. We show that a biofilm yeast colony is a finely tuned, complex \u2019multicellular organism, in which specialized cells jointly execute multiple protection strategies. These include a Pdr1p-regulated mechanism whereby multidrug-resistance transporters Pdr5p and Snq2p expel external compounds solely within the surface cell layers, as well as developmentally regulated production by internal cells of a selectively permeable extracellular matrix. The two mechanisms act in concert during colony development, allowing growth of new cell generations in a well protected, internal cavity of the colony. Colony architecture is strengthened by intercellular fiber connections"@en . . . "V\u00E1chov\u00E1, Libu\u0161e" . . "0021-9525" . "Journal of Cell Biology" . "The molecular mechanisms underlying the spatiotemporal development and environmental resistance of biofilms and colonies remain largely unknown. We show that a biofilm yeast colony is a finely tuned, complex \u2019multicellular organism, in which specialized cells jointly execute multiple protection strategies. These include a Pdr1p-regulated mechanism whereby multidrug-resistance transporters Pdr5p and Snq2p expel external compounds solely within the surface cell layers, as well as developmentally regulated production by internal cells of a selectively permeable extracellular matrix. The two mechanisms act in concert during colony development, allowing growth of new cell generations in a well protected, internal cavity of the colony. Colony architecture is strengthened by intercellular fiber connections" . . . . "194" . "\u0160\u0165ov\u00ED\u010Dek, V." . . "[A0EFE1BBAC22]" . . "000294602500006" .