"RIV/67985823:_____/10:00345059!RIV11-MSM-67985823" . . "275812700004" . . "259933" . "38" . . "9"^^ . "Koivisto, H." . . "Functional cholinergic damage develops with amyloid accumulation in young adult APPswe/PS1dE9 transgenic mice" . "Smy\u010Dkov\u00E1, Helena" . . . . . . . . "RIV/67985823:_____/10:00345059" . . "Machov\u00E1, Eva" . . "4"^^ . . "US - Spojen\u00E9 st\u00E1ty americk\u00E9" . . "Neurobiology of Disease" . . "Rudajev, Vladim\u00EDr" . "We investigated the functional characteristics of pre- and postsynaptic cholinergic transmission in APPswe/PS1dE9 double transgenic mice at a young age (7-10 weeks) before the onset of amyloid plaque formation and at adult age (5-6 months) at its onset. Our results indicate that functional pre- and postsynaptic cholinergic deficits are nor present in APPswe/PS1dE9 transgenic mice before 10 weeks of age, but develop along with beta-amyloid accumulation in the brain"@en . . "Functional cholinergic damage develops with amyloid accumulation in young adult APPswe/PS1dE9 transgenic mice" . . "1" . . "Dole\u017Eal, Vladim\u00EDr" . "Functional cholinergic damage develops with amyloid accumulation in young adult APPswe/PS1dE9 transgenic mice"@en . . "Alzheimer\u00B4s disease; acetylcholine release; amyloid"@en . "Functional cholinergic damage develops with amyloid accumulation in young adult APPswe/PS1dE9 transgenic mice"@en . "Tanila, H." . "[28A37C628E56]" . "0969-9961" . "6"^^ . "We investigated the functional characteristics of pre- and postsynaptic cholinergic transmission in APPswe/PS1dE9 double transgenic mice at a young age (7-10 weeks) before the onset of amyloid plaque formation and at adult age (5-6 months) at its onset. Our results indicate that functional pre- and postsynaptic cholinergic deficits are nor present in APPswe/PS1dE9 transgenic mice before 10 weeks of age, but develop along with beta-amyloid accumulation in the brain" . . "P(IAA500110703), P(LC554), Z(AV0Z50110509)" .