"\u00DA\u010Dinek N-acetylcysteinu a melatoninu i dosp\u011Bl\u00FDch spont\u00E1nn\u011B hypertenzn\u00EDch potkan\u016F s rozvinutou hypertenz\u00ED"@cs . "P(GA305/03/0769), P(NR7786), Z(AV0Z5011922)" . "The effect of N-acetylcysteine and melatonin in adult spontaneously hypertensive rats with established hypertension" . "Koj\u0161ov\u00E1, S." . "8"^^ . "Dobe\u0161ov\u00E1, Zdenka" . . . . . . "US - Spojen\u00E9 st\u00E1ty americk\u00E9" . "Attenuated NO formation and increased ROS formation are often found in human and experimental hypertension. Two antioxidants (NAC and melatonin) were chronically administered to SHR with established hypertension. Both treatments improved NO/ROS balance, but only melatonin lowered blood pressure. This indicates that antihypertensive effects of melatonin are independent of NO pathways" . "Attenuated NO formation and increased ROS formation are often found in human and experimental hypertension. Two antioxidants (NAC and melatonin) were chronically administered to SHR with established hypertension. Both treatments improved NO/ROS balance, but only melatonin lowered blood pressure. This indicates that antihypertensive effects of melatonin are independent of NO pathways"@en . . . "[683B887E4886]" . "European Journal of Pharmacology" . "561" . "Paulis, \u013Dudov\u00EDt" . "Sn\u00ED\u017Eena tvorba NO a zv\u00FD\u0161en\u00E1 produkce kysl\u00EDkov\u00FDch radik\u00E1l\u016F jsou \u010Dasto pozorov\u00E1ny u lidsk\u00E9 i experiment\u00E1ln\u00ED hypertenze. Spont\u00E1nn\u011B hypertenzn\u00ED potkani s rozvinutou hypertenz\u00ED dost\u00E1vali chronicky dv\u011B r\u016Fzn\u00E1 antioxidancia \u2013 NAC a melatonin. Ob\u011B l\u00E1tky zlep\u0161ovaly rovnov\u00E1hu NO a kysl\u00EDkov\u00FDch radik\u00E1l\u016F, ale krevn\u00ED tlak byl sni\u017Eov\u00E1n pouze melatoninem. To nazna\u010Duje, \u017Ee antihypertenzn\u00ED \u00FA\u010Dinky melatoninu jsou nez\u00E1visl\u00E9 na zm\u011Bn\u00E1ch tvorby NO"@cs . "The effect of N-acetylcysteine and melatonin in adult spontaneously hypertensive rats with established hypertension"@en . "The effect of N-acetylcysteine and melatonin in adult spontaneously hypertensive rats with established hypertension" . . "The effect of N-acetylcysteine and melatonin in adult spontaneously hypertensive rats with established hypertension"@en . . . "Zenebe, W." . "419017" . . . "Jendekov\u00E1, L." . "Zicha, Josef" . . "Kune\u0161, Jaroslav" . "NO synthase; oxidative load; genetic hypertension"@en . "129;136" . . "\u0160imko, F." . "Sl\u00E1dkov\u00E1, M." . "Dovinov\u00E1, I." . . . "11"^^ . "1-3" . "RIV/67985823:_____/07:00080986!RIV07-MZ0-67985823" . . "\u00DA\u010Dinek N-acetylcysteinu a melatoninu i dosp\u011Bl\u00FDch spont\u00E1nn\u011B hypertenzn\u00EDch potkan\u016F s rozvinutou hypertenz\u00ED"@cs . . "5"^^ . "Paulis, \u013Dudov\u00EDt" . . . . "0014-2999" . "Pech\u00E1\u0148ov\u00E1, Olga" . "RIV/67985823:_____/07:00080986" .