"US - Spojen\u00E9 st\u00E1ty americk\u00E9" . "Ahtoniemi, T." . . "[E42EBD47FC6D]" . "Harris-White, M. E." . . "Ort, Michael" . "beta-Amyloid infusion results in delayed and age-dependent learning deficits without role of inflammation or beta-amyloid deposits" . "beta-Amyloid infusion results in delayed and age-dependent learning deficits without role of inflammation or beta-amyloid deposits" . . "RIV/67985823:_____/06:00054429!RIV07-AV0-67985823" . . "T\u00E4htivaara, L." . "Laatikainen, R." . . "Goldsteins, G." . "beta-Amyloid infusion results in delayed and age-dependent learning deficits without role of inflammation or beta-amyloid deposits"@en . "Proceedings of the National Academy of Sciences of the United States of America" . . "beta-Amyloid infusion results in delayed and age-dependent learning deficits without role of inflammation or beta-amyloid deposits"@en . "Miettinen, T. K." . "Yrj\u00E4nheikki, J." . . . "8852;8857" . "466760" . "Leskinen, S." . "Jukarainen, N." . . "Learning deficit after the infusion of beta-amyloid into the rat brain is delayed and age dependent. The impairment corerelates with the decrease of some cerebrospinal fluid metabolites, but does not correlate with the appearing of amyloid plaques. Therefore even a subtle increase in brain beta-amyloid concentration may disrupt cognitive abilities in rats independent of inflammation or amyoid plaques load" . "Malm, T." . "Koistinaho, M." . "23" . . . "Nurmi, A." . "20"^^ . "Pussinen, R." . "Bure\u0161, Jan" . "6"^^ . "RIV/67985823:_____/06:00054429" . "Frautschy, S. A." . "Vartiainen, N." . "P(1M0517), P(GA309/06/1231), Z(AV0Z50110509)" . . "Zhor\u0161en\u00ED schopnosti se u\u010Dit se po inf\u016Fzi beta-amyloidu do mozku hlodavce se projev\u00ED a\u017E v del\u0161\u00EDm odstupu a je znateln\u00E9 jen u zv\u00ED\u0159at star\u00FDch. Zhor\u0161en\u00ED koreluje s poklesem n\u011Bkter\u00FDch metabolit\u016Fv v mozkom\u00ED\u0161n\u00EDm moku, nekoreluje v\u0161ak s v\u00FDskytem amyloidov\u00FDmi plaky. K po\u0161kozen\u00ED kognitivn\u00EDch schopnost\u00ED u hlodavc\u016F tud\u00ED\u017E vede i mal\u00E9 zv\u00FD\u0161en\u00ED koncentrace beta-amyloidu v mozku ani\u017E vznikne z\u00E1n\u011Bt nebo vzniknou amyloidov\u00E1 depozita"@cs . "Kanninen, K." . "2"^^ . "Koistinaho, J." . . "Inf\u00FAzn\u00ED pod\u00E1n\u00ED beta-Amyloidu vede k pozdn\u00EDmu a v\u011Bkov\u011B z\u00E1visl\u00E9mu po\u0161kozen\u00ED schopnosti se u\u010Dit, a to i bez vlivu z\u00E1n\u011Btu anebo beta-amyloidov\u00FDch depozit"@cs . . "0027-8424" . . "Puoliv\u00E4li, J." . . "103" . . "Inf\u00FAzn\u00ED pod\u00E1n\u00ED beta-Amyloidu vede k pozdn\u00EDmu a v\u011Bkov\u011B z\u00E1visl\u00E9mu po\u0161kozen\u00ED schopnosti se u\u010Dit, a to i bez vlivu z\u00E1n\u011Btu anebo beta-amyloidov\u00FDch depozit"@cs . . "Learning deficit after the infusion of beta-amyloid into the rat brain is delayed and age dependent. The impairment corerelates with the decrease of some cerebrospinal fluid metabolites, but does not correlate with the appearing of amyloid plaques. Therefore even a subtle increase in brain beta-amyloid concentration may disrupt cognitive abilities in rats independent of inflammation or amyoid plaques load"@en . "cerebrospinal fluid; learning; Alzheimer\u00B4s disease"@en . .