"5"^^ . "Bergamini, C." . . . . . "Inhibition of glycerophosphate-dependent H2O2 generation in brown fat mitochondria by idebenone" . "Inhibition of glycerophosphate-dependent H2O2 generation in brown fat mitochondria by idebenone" . "339" . "Ochrann\u00FD \u00FA\u010Dinek analog\u016F koenzymu Q je z\u00E1visl\u00FD na m\u00EDst\u011B vzniku reaktivn\u00EDch kysl\u00EDkov\u00FDch radik\u00E1l\u016F. Jedn\u00EDm z t\u011Bchto analog\u016F je idebenon, kter\u00FD je vyu\u017E\u00EDv\u00E1n pro l\u00E9\u010Debn\u00E9 \u00FA\u010Dely. Testovali jsme jeho ochrann\u00FD vliv na glycerolfosf\u00E1tem-z\u00E1vislou produkci reaktivn\u00EDch kysl\u00EDkov\u00FDch radik\u00E1l\u016F. Zjistili jsme, \u017Ee idebenon inhibuje jak glycerolfosf\u00E1tem-z\u00E1vislou tak sukcin\u00E1tem-z\u00E1vislou produkci reaktivn\u00EDch kysl\u00EDkov\u00FDch radik\u00E1l\u016F. Idebenon a koenzym Q1 byly \u00FA\u010Dinn\u011Bj\u0161\u00ED ne\u017E koenzym Q3"@cs . . "4"^^ . "RIV/67985823:_____/06:00041293!RIV07-AV0-67985823" . "Inhibice glycerolfosf\u00E1t-z\u00E1visl\u00E9 produkce peroxidu vod\u00EDku v mitochondri\u00EDch hn\u011Bd\u00E9ho tuku idebenonem"@cs . . "362;366" . . . "Drahota, Zden\u011Bk" . "Rauchov\u00E1, Hana" . . . "7"^^ . "0006-291X" . . . . "Biochemical and Biophysical Research Communications" . "Inhibice glycerolfosf\u00E1t-z\u00E1visl\u00E9 produkce peroxidu vod\u00EDku v mitochondri\u00EDch hn\u011Bd\u00E9ho tuku idebenonem"@cs . . . . . "P(1M0510), P(1M0520), P(GA303/03/0799), P(GA305/04/0500), Z(AV0Z50110509)" . "The protective effect of coenzyme Q analogs is dependent on the location of reactive oxygen species generation. One of these analogs, idebenone, is used as an antioxidative therapeutic drug. We tested its scavenging effect on glycerophosphate-dependent reactive oxygen species generation. We observed that idebenone inhibits both glycerophosphate\u2013 and succinate-dependent reactive oxygen species generation. Idebenone and coenzyme Q1 were found to be more efficient in the scavenging activity than coenzyme Q3"@en . . "mitochondrial glycerophosphate dehydrogenase; succinate dehydrogenase; coenzyme Q analogs"@en . "RIV/67985823:_____/06:00041293" . "Vrback\u00FD, Marek" . . "Inhibition of glycerophosphate-dependent H2O2 generation in brown fat mitochondria by idebenone"@en . "Fato, R." . "Lenaz, G." . "The protective effect of coenzyme Q analogs is dependent on the location of reactive oxygen species generation. One of these analogs, idebenone, is used as an antioxidative therapeutic drug. We tested its scavenging effect on glycerophosphate-dependent reactive oxygen species generation. We observed that idebenone inhibits both glycerophosphate\u2013 and succinate-dependent reactive oxygen species generation. Idebenone and coenzyme Q1 were found to be more efficient in the scavenging activity than coenzyme Q3" . . "479719" . "US - Spojen\u00E9 st\u00E1ty americk\u00E9" . . "[10D610A19E1C]" . "Hou\u0161t\u011Bk, Josef" . . . "1" . "Inhibition of glycerophosphate-dependent H2O2 generation in brown fat mitochondria by idebenone"@en .