"Elevace proteinu S-100B u pacient\u016F s akutn\u00EDm koron\u00E1rn\u00EDm syndromem po resuscitaci je prediktorem nep\u0159\u00EDzniv\u00E9 neurologick\u00E9 progn\u00F3zy" . . . "Ro\u010Dn\u00ED incidence mimonemocni\u010Dn\u00ED srde\u010Dn\u00ED z\u00E1stavy se pohybuje kolem 90\u2013190 p\u0159\u00EDpad\u016F na 100 000 obyvatel. Limituj\u00EDc\u00EDm faktorem dal\u0161\u00ED progn\u00F3zy pacient\u016F po mimonemocni\u010Dn\u00ED z\u00E1stav\u011B b\u00FDv\u00E1 neurologick\u00FD stav pacient\u016F. Protein S-100B, produkt bun\u011Bk p\u0159ev\u00E1\u017En\u011B nervov\u00E9 soustavy, je gliov\u011B specifick\u00FD a je vyj\u00E1d\u0159en p\u0159edev\u0161\u00EDm u astrocyt\u016F. Bylo prok\u00E1z\u00E1no, \u017Ee po ob\u011Bhov\u00E9 z\u00E1stav\u011B jeho zv\u00FD\u0161en\u00E1 hladina koreluje s progn\u00F3zou pacient\u016F. C\u00EDlem pr\u00E1ce je stanovit hladinu proteinu S-100B ve skupin\u011B pacient\u016F s akutn\u00EDm infarktem myokardu bez ob\u011Bhov\u00E9 z\u00E1stavy a porovnat ji s hodnotou u pacient\u016F s akutn\u00EDm infarktem myokardu po mimonemocni\u010Dn\u00ED resuscitaci. Metodika: Celkem bylo vyhodnoceno 24 pacient\u016F po mimonemocni\u010Dn\u00ED resuscitaci pro malign\u00ED arytmii p\u0159i akutn\u00EDm koron\u00E1rn\u00EDm syndromu (AKS), v\u0161ichni byli l\u00E9\u010Deni m\u00EDrnou terapeutickou hypotermi\u00ED. Kontroln\u00ED skupinu tvo\u0159ilo 19 pacient\u016F s AKS. Vzorek ke stanoven\u00ED S-100B byl odebr\u00E1n ihned p\u0159i p\u0159ijet\u00ED. Neurologick\u00FD stav byl hodnocen podle CPC sk\u00F3re (Cerebral Performance Categories) p\u0159i propu\u0161t\u011Bn\u00ED, pacienti byli rozd\u011Blen\u00ED do 3 skupin: CPC1 \u2013 dobr\u00FD stav, CPC2 \u2013 st\u0159edn\u011B z\u00E1va\u017En\u00E9 neurologick\u00E9 posti\u017Een\u00ED, CPC3-5 \u2013 z\u00E1va\u017En\u00E9 neurologick\u00E9 posti\u017Een\u00ED, k\u00F3ma nebo smrt."@cs . "Klabene\u0161ov\u00E1, Iva" . "CZ - \u010Cesk\u00E1 republika" . . . "Dost\u00E1lov\u00E1, L." . "4" . "acute corornary syndrom"@en . "134097" . "Elevace proteinu S-100B u pacient\u016F s akutn\u00EDm koron\u00E1rn\u00EDm syndromem po resuscitaci je prediktorem nep\u0159\u00EDzniv\u00E9 neurologick\u00E9 progn\u00F3zy"@cs . "Hel\u00E1nov\u00E1, Kate\u0159ina" . . "7"^^ . . "Lokaj, Petr" . . . "Gimunov\u00E1, Olga" . "RIV/65269705:_____/12:#0001798" . "Elevace proteinu S-100B u pacient\u016F s akutn\u00EDm koron\u00E1rn\u00EDm syndromem po resuscitaci je prediktorem nep\u0159\u00EDzniv\u00E9 neurologick\u00E9 progn\u00F3zy" . "S-100B protein elevation in patients with the acute coronary syndrome after resuscitation is a predictor of adverse neurological prognosis"@en . "Poloczek, Martin" . . "\u010Cerm\u00E1kov\u00E1, Zdenka" . . "S-100B protein elevation in patients with the acute coronary syndrome after resuscitation is a predictor of adverse neurological prognosis"@en . "I, P(NS9894)" . "0042-773X" . . "Malaska, Jan" . . . . . . . "Toman, Ond\u0159ej" . . "\u0160pinar, Jind\u0159ich" . "Kala, Petr" . . "12"^^ . . "14"^^ . "Pa\u0159enica, Ji\u0159\u00ED" . . "58" . . . "Elevace proteinu S-100B u pacient\u016F s akutn\u00EDm koron\u00E1rn\u00EDm syndromem po resuscitaci je prediktorem nep\u0159\u00EDzniv\u00E9 neurologick\u00E9 progn\u00F3zy"@cs . "Vnit\u0159n\u00ED l\u00E9ka\u0159stv\u00ED" . "The annual incidence of out-of-hospital cardiac arrest is around 90\u2013190 cases per 100 000 inhabitants. The limiting factor for further prognosis of patients after out-of-hospital arrest is their neurological status. The S100B protein is mainly the nervous system cell\u2019s product, it\u2019s glial-specific and mostly expressed by astrocytes. It has been shown that after circulatory arrest its increased level correlates with the prognosis of patients. Work aims to determine the level of protein S100B in the group of patients with acute myocardial infarction without circulatory arrest, and compare it to the value in patients with acute myocardial infarction after out-of-hospital resuscitation."@en . "Ro\u010Dn\u00ED incidence mimonemocni\u010Dn\u00ED srde\u010Dn\u00ED z\u00E1stavy se pohybuje kolem 90\u2013190 p\u0159\u00EDpad\u016F na 100 000 obyvatel. Limituj\u00EDc\u00EDm faktorem dal\u0161\u00ED progn\u00F3zy pacient\u016F po mimonemocni\u010Dn\u00ED z\u00E1stav\u011B b\u00FDv\u00E1 neurologick\u00FD stav pacient\u016F. Protein S-100B, produkt bun\u011Bk p\u0159ev\u00E1\u017En\u011B nervov\u00E9 soustavy, je gliov\u011B specifick\u00FD a je vyj\u00E1d\u0159en p\u0159edev\u0161\u00EDm u astrocyt\u016F. Bylo prok\u00E1z\u00E1no, \u017Ee po ob\u011Bhov\u00E9 z\u00E1stav\u011B jeho zv\u00FD\u0161en\u00E1 hladina koreluje s progn\u00F3zou pacient\u016F. C\u00EDlem pr\u00E1ce je stanovit hladinu proteinu S-100B ve skupin\u011B pacient\u016F s akutn\u00EDm infarktem myokardu bez ob\u011Bhov\u00E9 z\u00E1stavy a porovnat ji s hodnotou u pacient\u016F s akutn\u00EDm infarktem myokardu po mimonemocni\u010Dn\u00ED resuscitaci. Metodika: Celkem bylo vyhodnoceno 24 pacient\u016F po mimonemocni\u010Dn\u00ED resuscitaci pro malign\u00ED arytmii p\u0159i akutn\u00EDm koron\u00E1rn\u00EDm syndromu (AKS), v\u0161ichni byli l\u00E9\u010Deni m\u00EDrnou terapeutickou hypotermi\u00ED. Kontroln\u00ED skupinu tvo\u0159ilo 19 pacient\u016F s AKS. Vzorek ke stanoven\u00ED S-100B byl odebr\u00E1n ihned p\u0159i p\u0159ijet\u00ED. Neurologick\u00FD stav byl hodnocen podle CPC sk\u00F3re (Cerebral Performance Categories) p\u0159i propu\u0161t\u011Bn\u00ED, pacienti byli rozd\u011Blen\u00ED do 3 skupin: CPC1 \u2013 dobr\u00FD stav, CPC2 \u2013 st\u0159edn\u011B z\u00E1va\u017En\u00E9 neurologick\u00E9 posti\u017Een\u00ED, CPC3-5 \u2013 z\u00E1va\u017En\u00E9 neurologick\u00E9 posti\u017Een\u00ED, k\u00F3ma nebo smrt." . "RIV/65269705:_____/12:#0001798!RIV13-MZ0-65269705" . . . . "[DE3BE310972C]" .