. "Galactomannan detection in bronchoalveolar lavage fluid for the diagnosis of invasive aspergillosis in patients with hematological deseases-the role of factors affecting assay performance"@en . . . . "Galactomannan detection in bronchoalveolar lavage fluid for the diagnosis of invasive aspergillosis in patients with hematological deseases-the role of factors affecting assay performance" . "Sk\u0159i\u010Dkov\u00E1, Jana" . . "8"^^ . "International Journal of Infectious Diseases" . . . "hematological malignancy"@en . "R\u00E1\u010Dil, Zden\u011Bk" . . "I, P(NS10441), P(NS10442)" . "Mayer, Ji\u0159\u00ED" . "RIV/65269705:_____/11:#0001225!RIV12-MZ0-65269705" . "15" . "12" . "To\u0161kov\u00E1, Martina" . . "Volfov\u00E1, Pavl\u00EDna" . . "Rolencov\u00E1, Monika" . . "000298114700014" . "We evaluated the performance of a galactomannan (GM) assay in bronchoalveolar lavage (BAL) fluid compared to serum samples for the diagnosis of invasive pulmonary aspergillosis (IPA) in patients with hematological diseases. Results: Twenty-eight cases of IPA (11%) were diagnosed. The highest sensitivity (78.6%) with good specificity (98.6%) was obtained with a triple detection of GM in bronchial, alveolar, and serum samples. Neutropenia and antifungal therapy for only 24 h increased the sensitivity, while antifungal treatment for more than 2 days decreased assay performance.Conclusions: In contrast to recently published data, we found only moderate sensitivity, but high specificity and high positive predictive value of the detection of GM in BAL fluid."@en . . . . . . "Galactomannan detection in bronchoalveolar lavage fluid for the diagnosis of invasive aspergillosis in patients with hematological deseases-the role of factors affecting assay performance" . . . "200779" . "We evaluated the performance of a galactomannan (GM) assay in bronchoalveolar lavage (BAL) fluid compared to serum samples for the diagnosis of invasive pulmonary aspergillosis (IPA) in patients with hematological diseases. Results: Twenty-eight cases of IPA (11%) were diagnosed. The highest sensitivity (78.6%) with good specificity (98.6%) was obtained with a triple detection of GM in bronchial, alveolar, and serum samples. Neutropenia and antifungal therapy for only 24 h increased the sensitivity, while antifungal treatment for more than 2 days decreased assay performance.Conclusions: In contrast to recently published data, we found only moderate sensitivity, but high specificity and high positive predictive value of the detection of GM in BAL fluid." . "Weinbergerov\u00E1, Barbora" . "11"^^ . . "Hrn\u010D\u00ED\u0159ov\u00E1, Krist\u00FDna" . "Winterov\u00E1, Jana" . "Kocmanov\u00E1, Iva" . . "1201-9712" . . "[9764573F913C]" . "RIV/65269705:_____/11:#0001225" . . "12"^^ . . . "GB - Spojen\u00E9 kr\u00E1lovstv\u00ED Velk\u00E9 Brit\u00E1nie a Severn\u00EDho Irska" . . "Galactomannan detection in bronchoalveolar lavage fluid for the diagnosis of invasive aspergillosis in patients with hematological deseases-the role of factors affecting assay performance"@en . . "Lengerov\u00E1, Martina" . "10.1016/j.ijid.2011.09.011" .