. . "A118G polymorphism of OPRM1 gene is associated with schizophrenia"@en . . "000275905400028" . . "A118G polymorphism of OPRM1 gene is associated with schizophrenia" . "A118G polymorphism of OPRM1 gene is associated with schizophrenia" . "1" . . . "RIV/65269705:_____/10:#0001054!RIV11-MZ0-65269705" . . "RIV/65269705:_____/10:#0001054" . . "[1B339AD1DFF9]" . . "Schizophrenia is ranked among multifactor diseases in whose pathogenesis, besides environmental factors, an interplay of functional polymorphisms of a larger number of candidate genes is involved. Neurodevelopmental abnormities are among the most accepted hypotheses in the etiology of schizophrenia. Recently, the role of oligodendrocytes in the development of the cortex has been cited repeatedly. During their various phases of differentiation oligodendrocytes present on their surfaces diverse receptors, among others the mu-opioid receptor (OPRM1). The study was focused on the relationship between the functional A118G polymorphism of the OPRM1 gene (rs1799971) and schizophrenia in groups of 130 male patients and 452 male controls. An association study revealed yet unpublished statistically significant difference of allelic and genotypic frequencies between the control and patient groups." . "\u0160er\u00FD, Omar" . "schizophrenia"@en . "4"^^ . "US - Spojen\u00E9 st\u00E1ty americk\u00E9" . . . "4"^^ . "248326" . "Journal of Molecular Neuroscience" . "1"^^ . "41" . "P(NR9298), S, Z(MSM0021622413)" . "A118G polymorphism of OPRM1 gene is associated with schizophrenia"@en . . . "Schizophrenia is ranked among multifactor diseases in whose pathogenesis, besides environmental factors, an interplay of functional polymorphisms of a larger number of candidate genes is involved. Neurodevelopmental abnormities are among the most accepted hypotheses in the etiology of schizophrenia. Recently, the role of oligodendrocytes in the development of the cortex has been cited repeatedly. During their various phases of differentiation oligodendrocytes present on their surfaces diverse receptors, among others the mu-opioid receptor (OPRM1). The study was focused on the relationship between the functional A118G polymorphism of the OPRM1 gene (rs1799971) and schizophrenia in groups of 130 male patients and 452 male controls. An association study revealed yet unpublished statistically significant difference of allelic and genotypic frequencies between the control and patient groups."@en . . "0895-8696" . . . "P\u0159ikryl, Radovan" .