"Mnoho\u010Detn\u00FD myelom (MM) je pokl\u00E1d\u00E1n za nel\u00E9\u010Diten\u00E9 a m\u00E1lo imunogenn\u00ED onemocn\u011Bn\u00ED. Byly u\u010Din\u011Bny pokusy zm\u011Bnit imunitn\u00ED stav tak, aby byly rozpozn\u00E1nyl myelomov\u00E9 bu\u0148ky prost\u0159ednictv\u00EDm bun\u011Bk vlastn\u00EDho imunitn\u00EDho syst\u00E9mu. V na\u0161em projektu jsme studovali mo\u017Enost identifikace myelom-specifick\u00FDch T bub\u011Bk in vitro, jejich expanzi v klinicky vyu\u017Eiteln\u00FDch podm\u00EDnk\u00E1ch a specifickou cytotoxicitu expandovan\u00FDch T bun\u011Bk v\u016F\u010Di myelomov\u00FDm bu\u0148k\u00E1m."@cs . "0390-6078" . . . "[94D22B59FB6B]" . "6"^^ . "90" . "Bun\u011B\u010Dn\u00E1 imunoterapie u mnoho\u010Detn\u00E9ho myelomu : Identifikace a in vitro expanze myelom-specifick\u00FDch T bun\u011Bk"@cs . "Multiple myeloma has been considered as low immunogenic incurable disease. The attempts has been made to invert the immune status to recognize myeloma cells by T cells or other cell sof the immune syst\u00E9m.Here we studied the posibility of identification of myeloma-specific T cells in vitro, thein clinical-grade expansion, and specific cytotoxicity of expanded T cells to myeloma cells." . "P(NC7475)" . "IT - Italsk\u00E1 republika" . . . "Mich\u00E1lek, Jaroslav" . . "H\u00E1jek, Roman" . . . "Cell immunotherapy of multiple myeloma: Identification andin vitro expansion of myeloma-specific T cells" . "Cell immunotherapy of multiple myeloma: Identification andin vitro expansion of myeloma-specific T cells" . "514597" . "Zahradov\u00E1, Lenka" . "184-184" . . . . "cell immunotherapy; multiple myeloma; myeloma-specific T cells; in vitro expansion"@en . "RIV/65269705:_____/05:#0000010" . . "Cell immunotherapy of multiple myeloma: Identification andin vitro expansion of myeloma-specific T cells"@en . . "Penka, Miroslav" . "Bun\u011B\u010Dn\u00E1 imunoterapie u mnoho\u010Detn\u00E9ho myelomu : Identifikace a in vitro expanze myelom-specifick\u00FDch T bun\u011Bk"@cs . "RIV/65269705:_____/05:#0000010!RIV06-MZ0-65269705" . . . "Kov\u00E1\u0159ov\u00E1, Lucie" . . "Multiple myeloma has been considered as low immunogenic incurable disease. The attempts has been made to invert the immune status to recognize myeloma cells by T cells or other cell sof the immune syst\u00E9m.Here we studied the posibility of identification of myeloma-specific T cells in vitro, thein clinical-grade expansion, and specific cytotoxicity of expanded T cells to myeloma cells."@en . "O\u010Dadl\u00EDkov\u00E1, Darina" . . . . "Cell immunotherapy of multiple myeloma: Identification andin vitro expansion of myeloma-specific T cells"@en . . "1"^^ . . . "Haematologica/the hematology journal" . "S1" . "6"^^ .