"9"^^ . "Cs\u00F6llei, Jozef" . "Mal\u00EDk, Ivan" . "[D1916A031D47]" . "303496" . "Andriamainty, Fils" . . "5"^^ . . . . . "\u010Ci\u017Em\u00E1rik, Jozef" . "Antimycobacterial activity; Antituberculotic activity; Arylcarbonyloxyaminopropanols; Lipophilicity; Phenylcarbamates; Potential antituberculotics"@en . "Antimycobacterial activity of novel derivatives of arylcarbonyloxyaminopropanols"@en . . . "The study examined the antimicrobial activity of 2-hydroxy-3-[4-(2-fluoro, 4-fluoro, and 2-metoxyphenyl)-piperazin-l-yl]-propyl- 4-[(alkoxycarbonyl)amino] benzoates, their salts with hydrochloric acid, with one to four carbon atoms in the alkoxy group of the carbamoyl group studied and described. The series of these substances were evaluated in vitro against Mycobacterium kansasii 6 509/96. The correlation of this activity with lipophilicity (log k') was used to describe the structure-antimycobacterial activity relationships (QSARs). The tests have shown that practically all the substances under study possess antituberculotic activity. In vitro antimycobacterial activity increased with increasing lipophilicity. According to the obtained results, the substances can be considered as potential antituberculotics."@en . "1210-7816" . "Antimycobacterial activity of novel derivatives of arylcarbonyloxyaminopropanols"@en . "The study examined the antimicrobial activity of 2-hydroxy-3-[4-(2-fluoro, 4-fluoro, and 2-metoxyphenyl)-piperazin-l-yl]-propyl- 4-[(alkoxycarbonyl)amino] benzoates, their salts with hydrochloric acid, with one to four carbon atoms in the alkoxy group of the carbamoyl group studied and described. The series of these substances were evaluated in vitro against Mycobacterium kansasii 6 509/96. The correlation of this activity with lipophilicity (log k') was used to describe the structure-antimycobacterial activity relationships (QSARs). The tests have shown that practically all the substances under study possess antituberculotic activity. In vitro antimycobacterial activity increased with increasing lipophilicity. According to the obtained results, the substances can be considered as potential antituberculotics." . "58" . . "5-6" . . "S" . . . "Mokr\u00FD, Petr" . . "2"^^ . . "Antimycobacterial activity of novel derivatives of arylcarbonyloxyaminopropanols" . "Ke\u010Dk\u00E9\u0161ov\u00E1, Simona" . . . "RIV/62157124:16370/09:00002079" . "CZ - \u010Cesk\u00E1 republika" . "RIV/62157124:16370/09:00002079!RIV10-MSM-16370___" . "Kaustov\u00E1, Jarmila" . . "Garaj, Vladim\u00EDr" . "Sedl\u00E1rov\u00E1, Eva" . . "Antimycobacterial activity of novel derivatives of arylcarbonyloxyaminopropanols" . "\u010Cesk\u00E1 a slovensk\u00E1 farmacie" . . "16370" .