"Automatic building of nucleic acids structures" . "16370" . . . "Automatic building of nucleic acids structures"@en . . "Automatic building of nucleic acids structures"@en . . . "466392" . "S" . . "Automatick\u00E1 tvorba struktur nukleov\u00FDch kyselin"@cs . "Molecular fragments are located in an electron density map by a phased rotation conformation and translation function, as implemented in the program NUT [1]. Two types of backbone fragments can be used.Arigid double helical fragment NAhelix of 90 atoms is used to locate stretches of regularA-RNA (DNA) structures. The position and orientation of the fragment can be refined. NAhelix is suitable for low-resolution structures. Typical RNA structure contains about 70% of the double-helical conformation. The second fragment is RNAbone (17 atoms), which represents mononucleotide of phosphate-sugar- phosphate type. The fragment is flexible and all backbone torsion angles can be varied during the search. For computation reasons the search is restricted by a table of allowed conformations. The most frequent conformations were determined by a conformation family generator [2] utilizing knowledge of sugar-phosphate-sugar conformation families [3]. The RNAbone is suitable for intermediate resolutio"@en . . . "2006-08-06+02:00"^^ . . "2"^^ . . . . "Pavel\u010D\u00EDk, Franti\u0161ek" . . "2006-08-11+02:00"^^ . "495"^^ . "Molekul\u00E1rn\u00ED fragmenty byly um\u00EDst\u011Bny do mapy elektronov\u00E9 hustoty tak, jak je obvykl\u00E9 v programu NUT. Bylo mo\u017Eno pou\u017E\u00EDt 2 typy p\u00E1te\u0159n\u00EDch fragment\u016F: rigidn\u00ED dvojit\u011B helik\u00E1ln\u00ED fragment pro modelov\u00E1n\u00ED \u00FAsek\u016F A-RNA nebo DNA a flexibiln\u00ED fragment RNA, kter\u00FD p\u0159edstavuje mononukleotid typu fosf\u00E1t-cukr-fosf\u00E1t. Byly nalezeny nejpravd\u011Bpodobn\u011Bj\u0161\u00ED konformace, vytvo\u0159en model polyribonukleotidov\u00E9ho \u0159et\u011Bzce a modely byly d\u00E1le testov\u00E1ny."@cs . "[17B1DB7D2C6C]" . "1"^^ . . "RIV/62157124:16370/06:00000738" . "500"^^ . "Molecular fragments are located in an electron density map by a phased rotation conformation and translation function, as implemented in the program NUT [1]. Two types of backbone fragments can be used.Arigid double helical fragment NAhelix of 90 atoms is used to locate stretches of regularA-RNA (DNA) structures. The position and orientation of the fragment can be refined. NAhelix is suitable for low-resolution structures. Typical RNA structure contains about 70% of the double-helical conformation. The second fragment is RNAbone (17 atoms), which represents mononucleotide of phosphate-sugar- phosphate type. The fragment is flexible and all backbone torsion angles can be varied during the search. For computation reasons the search is restricted by a table of allowed conformations. The most frequent conformations were determined by a conformation family generator [2] utilizing knowledge of sugar-phosphate-sugar conformation families [3]. The RNAbone is suitable for intermediate resolutio" . "Schneider, Bohuslav" . "nucleic acids; model building; automatic structure solution"@en . "RIV/62157124:16370/06:00000738!RIV07-MSM-16370___" . "Automatic building of nucleic acids structures" . . "Leuven" . "Automatick\u00E1 tvorba struktur nukleov\u00FDch kyselin"@cs . .