"Outbreak of mycoplasmosis in the grey partridge: histopathology, biochemistry and oxidative stress responses"@en . . . . "Z(MSM6215712402)" . "978-80-8077-230-7" . "The objective of this study was to describe the outbreak, pathology, and blood and tissue biochemical responses in a flock of grey partridges naturally infected with Mycoplasma gallisepticum. Morbidity and mortality rates were 100% and 60%, respectively. Necropsy revealed an accumulation of caseous exudate within the infraorbital sinuses, tracheitis, pneumonia and airsacculitis. There were significant increases in activities of lactate dehydrogenase, creatine kinase and amylase, and levels of total protein and glucose in Mycoplasma-infected birds when compared to control. Catalase showed significantly lower activity in the heart, lungs, liver and gonads of Mycoplasma-infected birds. Glutathione-S-transferase activity was elevated in the eye and the associated infraorbital sinus and kidneys, and decreased in the liver. Decreased levels of reduced glutathione were found in the heart, kidneys, liver and gonads. The activity of glutathione reductase was lower only in the lungs. Compared to healthy birds, mycoplasmosis in the grey partridge caused significant differences in the level of lipid peroxidation in lungs and plasma (p{0.05), while the ferric reducing antioxidant power was lower in the heart and kidneys (p{0.01). Significant correlations among responses of the antioxidant parameters were found namely in the heart, lungs, spleen, liver and plasma. There were also numerous significant inter-tissue correlations of all the studied antioxidant parameters. The present study demonstrates the high susceptibility of grey partridges to natural infection by M. gallisepticum, the severity of the disease based on histopathology, and the modulation of blood chemical profiles and oxidative stress-associated parameters in the avian hosts, thus enhancing the understanding of the pathogenesis of mycoplasmosis in birds. Moreover, the reported reference values can be useful for the evaluation of the state of health in grey partridges."@en . . "Pikula, Ji\u0159\u00ED" . "Outbreak of mycoplasmosis in the grey partridge: histopathology, biochemistry and oxidative stress responses" . . "7"^^ . "The objective of this study was to describe the outbreak, pathology, and blood and tissue biochemical responses in a flock of grey partridges naturally infected with Mycoplasma gallisepticum. Morbidity and mortality rates were 100% and 60%, respectively. Necropsy revealed an accumulation of caseous exudate within the infraorbital sinuses, tracheitis, pneumonia and airsacculitis. There were significant increases in activities of lactate dehydrogenase, creatine kinase and amylase, and levels of total protein and glucose in Mycoplasma-infected birds when compared to control. Catalase showed significantly lower activity in the heart, lungs, liver and gonads of Mycoplasma-infected birds. Glutathione-S-transferase activity was elevated in the eye and the associated infraorbital sinus and kidneys, and decreased in the liver. Decreased levels of reduced glutathione were found in the heart, kidneys, liver and gonads. The activity of glutathione reductase was lower only in the lungs. Compared to healthy birds, mycoplasmosis in the grey partridge caused significant differences in the level of lipid peroxidation in lungs and plasma (p{0.05), while the ferric reducing antioxidant power was lower in the heart and kidneys (p{0.01). Significant correlations among responses of the antioxidant parameters were found namely in the heart, lungs, spleen, liver and plasma. There were also numerous significant inter-tissue correlations of all the studied antioxidant parameters. The present study demonstrates the high susceptibility of grey partridges to natural infection by M. gallisepticum, the severity of the disease based on histopathology, and the modulation of blood chemical profiles and oxidative stress-associated parameters in the avian hosts, thus enhancing the understanding of the pathogenesis of mycoplasmosis in birds. Moreover, the reported reference values can be useful for the evaluation of the state of health in grey partridges." . "13"^^ . "Rosenbergov\u00E1, Kate\u0159ina" . "Ondr\u00E1\u010Dek, Karel" . . . "Zendulkov\u00E1, Dagmar" . "16270" . "RIV/62157124:16270/11:43870799!RIV12-MSM-16270___" . "Ko\u0161ice" . . "219137" . "Ko\u0161ice" . "Novotn\u00FD, Ladislav" . . . . "Osi\u010Dkov\u00E1, Jitka" . "Proceedings of scientific contributions and abstracts Infectious and Parasitic Diseases of Animals" . "Univerzita veterin\u00E1rn\u00E9ho lek\u00E1rstva Ko\u0161ice" . . "Peckov\u00E1, Lucie" . . . "Outbreak of mycoplasmosis in the grey partridge: histopathology, biochemistry and oxidative stress responses"@en . "2011-09-07+02:00"^^ . "Vitula, Franti\u0161ek" . . . "Ban\u010Fouchov\u00E1, Hana" . "Outbreak of mycoplasmosis in the grey partridge: histopathology, biochemistry and oxidative stress responses" . . "Kr\u00E1l, Ji\u0159\u00ED" . . . . "RIV/62157124:16270/11:43870799" . "Treml, Franti\u0161ek" . . . . "Pohanka, Miroslav" . . . "[6C853DC17670]" . . "3"^^ . "oxidative stress; biochemistry; histopathology; natural infection; partridge; Mycoplasmosis"@en . "J\u00EDra, David" .