"horse; anaesthesia; salbutamol; oxygenation"@en . "Patschov\u00E1, M\u00E1ria" . "RIV/62157124:16170/08:00001892!RIV09-MSM-16170___" . . . "2008-10-15+02:00"^^ . . . "\u00DA\u010Dinek podan\u00ED salbutamolu na arteri\u00E1ln\u00ED oxygenaci a syst\u00E9movou dod\u00E1vku kysl\u00EDku b\u011Bhem celkov\u00E9 anest\u00E9zie u kon\u011B."@cs . . "\u00DA\u010Dinek podan\u00ED salbutamolu na arteri\u00E1ln\u00ED oxygenaci a syst\u00E9movou dod\u00E1vku kysl\u00EDku b\u011Bhem celkov\u00E9 anest\u00E9zie u kon\u011B."@cs . . . . "220"^^ . . "The aim of this experimental cross-over blinded study was to determine effect of aerosolised salbutamol administration on oxygen delivery during general anaesthesia. Previous studies using beta2 adrenergic agonists reported controversial results (Dodam et al., 1993; Robertson and Bailey, 2002). Six healthy Thoroughbreds (body weight range 470 - 587 kg) underwent two general anaesthesias in dorsal recumbency with and without aerosolised salbutamol administration in randomized order with one month washout period. The anaesthetic protocol included administration of 1.1 mg/kg of xylazine followed by 2.2 mg/kg of ketamine and 0.02 mg/kg of diazepam. Isoflurane was used for maintenance (FiO2 0.5-0.6). All horses were mechanically ventilated. FiO2, PaO2, cardiac output (lithium dilution) and arterial oxygen content (blood gas analysis and co-oximetry) were included. After steady state achievement (45 minutes) baseline values (T0) were recorded in salbutamol group (S-group) and control group (C-group) res" . "[3F757FB28AF6]" . . . "Z(MSM6215712403)" . . "The effect of salbutamol administration on arterial oxygenation and systemic oxygen delivery during general anaesthesia in the horse"@en . . "16170" . "The effect of salbutamol administration on arterial oxygenation and systemic oxygen delivery during general anaesthesia in the horse"@en . "365226" . "The effect of salbutamol administration on arterial oxygenation and systemic oxygen delivery during general anaesthesia in the horse" . . . "Spain" . "The effect of salbutamol administration on arterial oxygenation and systemic oxygen delivery during general anaesthesia in the horse" . "The aim of this experimental cross-over blinded study was to determine effect of aerosolised salbutamol administration on oxygen delivery during general anaesthesia. Previous studies using beta2 adrenergic agonists reported controversial results (Dodam et al., 1993; Robertson and Bailey, 2002). Six healthy Thoroughbreds (body weight range 470 - 587 kg) underwent two general anaesthesias in dorsal recumbency with and without aerosolised salbutamol administration in randomized order with one month washout period. The anaesthetic protocol included administration of 1.1 mg/kg of xylazine followed by 2.2 mg/kg of ketamine and 0.02 mg/kg of diazepam. Isoflurane was used for maintenance (FiO2 0.5-0.6). All horses were mechanically ventilated. FiO2, PaO2, cardiac output (lithium dilution) and arterial oxygen content (blood gas analysis and co-oximetry) were included. After steady state achievement (45 minutes) baseline values (T0) were recorded in salbutamol group (S-group) and control group (C-group) res"@en . "2008-10-16+02:00"^^ . . "1"^^ . "180"^^ . "RIV/62157124:16170/08:00001892" . . . "1"^^ . "C\u00EDlem t\u00E9to experiment\u00E1ln\u00ED cross-over studie je ur\u010Den\u00ED vlivu inhala\u010Dn\u00EDho pod\u00E1n\u00ED salbutamolu na dod\u00E1vku kysl\u00EDku b\u011Bhem celkov\u00E9 anest\u00E9zie. \u0160est zdrav\u00FDch anglick\u00FDch plnokrevn\u00EDk\u016F podstoupilo dv\u011B celkov\u00E9 anest\u00E9zie v dorz\u00E1ln\u00ED polohe, s a bez inhala\u010Dn\u00ED aplikace salbutamolu v n\u00E1hodn\u00E9m po\u0159ad\u00ED, s mes\u00ED\u010Dn\u00ED klidovou periodou mezi anest\u00E9ziemi. Anest\u00E9ziologick\u00FD protokol zahrnoval pod\u00E1n\u00ED 1.1 mg/kg xylazinu, 2.2 mg/kg ketaminu a 0.02 mg/kg diazepamu. Anest\u00E9zie byla veden\u00E1 izofluranem (FiO2 0.5-0.6). V\u0161echny kon\u011B byli mechanicky ventilovan\u00ED. Inhala\u010Dn\u011B podan\u00FD salbutamol u zdrav\u00FDch kon\u00ED b\u011Bhem celkov\u00E9 anest\u00E9zie m\u016F\u017Ee m\u00EDt pozitivn\u00ED vliv na arteri\u00E1ln\u00ED oxygen\u00E1ci a dod\u00E1vku kysl\u00EDku, ale efekt je variabiln\u00ED mezi jedinci."@cs .