"16170" . "412572" . . "359-363" . "1"^^ . "C\u00EDle: U opera\u010Dn\u00EDch seps\u00ED je pro p\u0159e\u017Eit\u00ED pacienta z\u00E1sadn\u00ED rychl\u00E1 identifikace zdroje infekce. Rozli\u0161en\u00ED mez\u00ED lok\u00E1ln\u00ED a generalizovanou infekc\u00ED je z\u00E1sadn\u00ED pro spr\u00E1vnou l\u00E9\u010Dbu. Metodika: v kontrolovan\u00E9 randomizovan\u00E9 studii v jednom centru jsme sledovali 72 pacient\u016F v t\u011B\u017Ek\u00E9 sepsi po abdomin\u00E1ln\u00EDm velk\u00E9m opera\u010Dn\u00EDm v\u00FDkonu nebo o\u0161et\u0159en\u00ED polytraumatu. Pacienti byly rozd\u011Bleni do 2 skupin: v prvn\u00ED skupin\u011B (PCT n=38) byl p\u0159ikl\u00E1d\u00E1n v\u011Bt\u0161\u00ED v\u00FDznam vy\u0161et\u0159en\u00ED hladiny PCT (t\u011B\u017Ek\u00E1 sepse s PCT v\u011Bt\u0161\u00ED 2 ng/ml signalizovala bacteremii a vedla ke zm\u011Bn\u011B ATB a v\u00FDm\u011Bn\u011B intravaskul\u00E1rn\u00EDch kanyl, t\u011B\u017Ek\u00E1 sepse s PCT men\u0161\u00ED nebo rovno 2 ng/ml n\u00E1s vedla k USG a/nebo CT n\u00E1sledovan\u00E1 reoperac\u00ED u pacient\u016F s lok\u00E1ln\u00ED infekc\u00ED). Kontroln\u00ED skupina (CON, n=34 byla l\u00E9\u010Den\u00E1 standardn\u00EDm vyhodnocen\u00EDm v\u0161ech parametr\u016F konzultac\u00ED s chirurgem). Sledovali jsme 28denn\u00ED mortalitu, komplikace sepse, dny na JIP, dny UPV. V\u00FDsledky: nemocni\u010Dn\u00ED mortalita byla u PCT skupiny 26 % a 38 % u CON (p=0,28). Pr\u016Fm\u011Brn\u00E9 SOFA sk\u00F3re bylo 7.9?2.8 u PCT skupiny vs. 9.3?"@cs . "Background/Aims: In surgical sepsis, the rapid identification of source of infection at an early stage after surgery or serious trauma is crucial for favorable outcome. The discrimination between local and generalized infection is critical for correct treatment. Methodology: In a randomized, controlled, single-centre study we investigated 72 patients with severe sepsis after major abdominal surgery or surgery of multiple trauma. Patiens were dividend in 2 groups: in the first group (PCT, n=38), more important role in the treatment decision was given to PCT level (severe sepsis with PCT > 2ng/ml signalized bacteremia and pushed us to change antibiotics and intravascular devices, severe sepsis with PCT <= 2 ng/ml prompted to ultrasonography and/or CT, followed by repeated surgery in patients with localized infection.) The control group (NOC, n=34) was treated by standard evaluation of all parameters by consultant surgeon. We investigated 28-day all-cause mortality, sepsis related complications," . "74" . . "RIV/62157124:16170/07:00001553" . . . . "Hepato-Gastroenterology" . . . "Scheer, Peter" . "Can procalcitonin help us in timing of re-intervention in septic patients after multiple trauma or major surgery?" . "Can procalcitonin help us in timing of re-intervention in septic patients after multiple trauma or major surgery?"@en . "0172-6390" . . "Svoboda, Petr" . "severe sepsis; microbiology"@en . "54" . "Radvanov\u00E1, Jana" . . "RIV/62157124:16170/07:00001553!RIV08-MZ0-16170___" . . "5"^^ . "M\u016F\u017Ee prokalcitonin pomoct v na\u010Dasov\u00E1n\u00ED reoperace u septick\u00FDch pacient\u016F po mnoho\u010Detn\u00E9m zran\u011Bn\u00ED nebo velk\u00E9m opera\u010Dn\u00EDm v\u00FDkonu?"@cs . . "5"^^ . . "GR - \u0158eck\u00E1 republika" . "P(ND7676)" . "Radvan, Martin" . "[F65C4EE104E0]" . . "Can procalcitonin help us in timing of re-intervention in septic patients after multiple trauma or major surgery?"@en . "Can procalcitonin help us in timing of re-intervention in septic patients after multiple trauma or major surgery?" . "Background/Aims: In surgical sepsis, the rapid identification of source of infection at an early stage after surgery or serious trauma is crucial for favorable outcome. The discrimination between local and generalized infection is critical for correct treatment. Methodology: In a randomized, controlled, single-centre study we investigated 72 patients with severe sepsis after major abdominal surgery or surgery of multiple trauma. Patiens were dividend in 2 groups: in the first group (PCT, n=38), more important role in the treatment decision was given to PCT level (severe sepsis with PCT > 2ng/ml signalized bacteremia and pushed us to change antibiotics and intravascular devices, severe sepsis with PCT <= 2 ng/ml prompted to ultrasonography and/or CT, followed by repeated surgery in patients with localized infection.) The control group (NOC, n=34) was treated by standard evaluation of all parameters by consultant surgeon. We investigated 28-day all-cause mortality, sepsis related complications,"@en . "Kantorov\u00E1, Ilona" . "M\u016F\u017Ee prokalcitonin pomoct v na\u010Dasov\u00E1n\u00ED reoperace u septick\u00FDch pacient\u016F po mnoho\u010Detn\u00E9m zran\u011Bn\u00ED nebo velk\u00E9m opera\u010Dn\u00EDm v\u00FDkonu?"@cs . .