. . "Ludv\u00EDkov\u00E1, Eva" . . . "Z(MSM 161700002), Z(MSM6215712403)" . . "Selenium and vitamin E status correlated with myopathies of horses reared in farms in the Czech Republic"@en . . . . . . . "The objective of the study was to compare selenium and vitamin E status in equine farms with and without occurrence of myopathies in order to evaluate the role of lack of these substances in the aetiology of myopathies in horses in the Czech Republic. Concentrations of selenium (in 136 horses) and vitamin E (in 131 horses) and glutathione peroxidase (GSH-Px) activities (in 136 horses) were measured in horses from farms with the occurrence of myopathies (group M including 46 horses from 10 farms) and in horses from farms without occurrence of myopathies (group H including 90 horses from 22 farms). Significantly lower concentrations of selenium (43.09 +/- 36.84 \u00B5g l-1; p < 0.001), vitamin E (9.55 +/- 9.29 \u00B5mol l-1; p < 0.01) and GSH-Px activities (153.38 +/- 177.28 \u00B5kat l-1; p < 0.001) were found in horses from the farms with the occurrence of myopathies when compared to those without the occurrence of myopathies (Se 117.35 +/- 52.10 \u00B5g l-1; vitamin E 10.75 +/- 4.34 \u00B5mol l-1; GSH-Px 397.41 +/-" . "Selenium and vitamin E status correlated with myopathies of horses reared in farms in the Czech Republic"@en . . "4"^^ . "Jahn, Petr" . "Vysko\u010Dil, Mirko" . "3"^^ . . . . "7"^^ . "16170" . "542193" . "Stav z\u00E1soben\u00ED selenem a vitaminem E v chovech kon\u00ED \u010Cesk\u00E9 republiky s v\u00FDskytem a bez v\u00FDskytu myopati\u00ED"@cs . "Selenium and vitamin E status correlated with myopathies of horses reared in farms in the Czech Republic" . . "Pavlata, Leo\u0161" . "Acta veterinaria Brno" . "CZ - \u010Cesk\u00E1 republika" . "Selenium and vitamin E status correlated with myopathies of horses reared in farms in the Czech Republic" . "0001-7213" . "Stav z\u00E1soben\u00ED selenem a vitaminem E v chovech kon\u00ED \u010Cesk\u00E9 republiky s v\u00FDskytem a bez v\u00FDskytu myopati\u00ED"@cs . "3" . . "C\u00EDlem pr\u00E1ce bylo porovnat stav z\u00E1soben\u00ED selenem a vitaminem E v chovech kon\u00ED s v\u00FDskytem a bez v\u00FDskytu myopati\u00ED a posoudit tak vliv z\u00E1soben\u00ED selenem a vitaminem E na vznik myopati\u00ED u kon\u00ED v \u010Cesk\u00E9 republice. U kon\u00ED poch\u00E1zej\u00EDc\u00EDch z chov\u016F s v\u00FDskytem myopati\u00ED - skupina M (46 kon\u00ED z 10 chov\u016F) i bez v\u00FDskytu myopati\u00ED - skupina H (90 kon\u00ED z 22 chov\u016F) byla stanovena koncentrace selenu (Se), aktivita glutathionperoxid\u00E1zy (GSH-Px) a koncentrace vitaminu E. V chovech kon\u00ED s v\u00FDskytem myopati\u00ED byla zji\u0161t\u011Bna pr\u016Fkazn\u011B ni\u017E\u0161\u00ED koncentrace selenu (43,09 +/- 36,84 \u00B5g l-1; p < 0,001), aktivita GSH-Px (153,38 +/- 177,28 \u00B5kat l-1; p < 0,001) i koncentrace vitaminu E (9,55 +/- 9,29 \u00B5mol l-1; p < 0,01) v porovn\u00E1n\u00ED s chovy kon\u00ED, kde se myopatie nevyskytovaly (Se 117,35 +/- 52,10 \u00B5g l-1; GSH-Px 397,41 +/- 242,15 \u00B5kat l-1; vit. E 10,75 +/- 4,34 \u00B5mol l-1). U \u0161esti kon\u00ED s myopati\u00ED byla stanovena diagn\u00F3za nutri\u010Dn\u00ED myodegenerace (WMD), u dal\u0161\u00EDch \u010Dty\u0159 kon\u00ED se jednalo pravd\u011Bpodobn\u011B o myopatii jin\u00E9 etiologie. Vyhodnocen\u00EDm cel\u00E9h"@cs . "[47AA2A4F1D81]" . "377-384" . "Glutathione peroxidase; nutritional myodegeneration; white muscle disease; tocopherol; creatine kinase; aspartate aminotransferase"@en . . . . "The objective of the study was to compare selenium and vitamin E status in equine farms with and without occurrence of myopathies in order to evaluate the role of lack of these substances in the aetiology of myopathies in horses in the Czech Republic. Concentrations of selenium (in 136 horses) and vitamin E (in 131 horses) and glutathione peroxidase (GSH-Px) activities (in 136 horses) were measured in horses from farms with the occurrence of myopathies (group M including 46 horses from 10 farms) and in horses from farms without occurrence of myopathies (group H including 90 horses from 22 farms). Significantly lower concentrations of selenium (43.09 +/- 36.84 \u00B5g l-1; p < 0.001), vitamin E (9.55 +/- 9.29 \u00B5mol l-1; p < 0.01) and GSH-Px activities (153.38 +/- 177.28 \u00B5kat l-1; p < 0.001) were found in horses from the farms with the occurrence of myopathies when compared to those without the occurrence of myopathies (Se 117.35 +/- 52.10 \u00B5g l-1; vitamin E 10.75 +/- 4.34 \u00B5mol l-1; GSH-Px 397.41 +/-"@en . "74" . . "RIV/62157124:16170/05:00000274!RIV06-MSM-16170___" . "RIV/62157124:16170/05:00000274" .