. . "[60513E2FA80D]" . . "Autochtonn\u00ED populace starokladrubsk\u00FDch kon\u00ED je pova\u017Eov\u00E1na za ohro\u017Een\u00E9 plemeno. Letn\u00ED dermatitida je alergickou reakc\u00ED na hmyz\u00ED bodnut\u00ED a objevuje se u t\u00E9to populace v z\u00E1vislosti na v\u00FDskytu specifick\u00FDch n\u00E1chyln\u00FDch genotyp\u016F. Testov\u00E1ny byly mikrosatelitn\u00ED markery i SNP polymorfismy."@cs . "Ho\u0159\u00EDn, P." . "Vrtkov\u00E1, Irena" . . "Putnov\u00E1, Lenka" . "Molecular and association analysis in an endangered breed: summer dermatitis in Old Kladruber horses" . "P(1G58073)" . "dermatitis; horse; microsatellites; SNP"@en . "434833" . . . "43210" . . . . "RIV/62156489:43210/07:00121242!RIV08-MZE-43210___" . . "Molekul\u00E1rn\u00ED a asocia\u010Dn\u00ED anal\u00FDzy u ohro\u017Een\u00E9ho plemene: dermatitida u starokladrubsk\u00FDch kon\u00ED"@cs . . "Molekul\u00E1rn\u00ED a asocia\u010Dn\u00ED anal\u00FDzy u ohro\u017Een\u00E9ho plemene: dermatitida u starokladrubsk\u00FDch kon\u00ED"@cs . "Molecular and association analysis in an endangered breed: summer dermatitis in Old Kladruber horses"@en . "2"^^ . . . "RIV/62156489:43210/07:00121242" . "3"^^ . . . "Molecular and association analysis in an endangered breed: summer dermatitis in Old Kladruber horses"@en . . "The autochtonous Old Kladruber horse is considered as an endangered breed. Due to it's isolation and small size, occurrence of various types of diseases may represent a serious threat implicating conservation issues. Summer dermatitis occurring also in the Old Kladruber grey population is an allergic reaction to insect bites, with possible involvement of specific susceptible genotypes. According to manifested clinical signs of summer dermatitis observed over last 8 years, 73 breeding mares were classified as susceptible and resistant, respectively. A combined approach was used to screen the genome for candidate chromosome regions and/or candidate genes. 50 microsatellites and 9 single nucleotide polymorphisms (SNPs) in 5 candidate genes, the lipopolysaccharide (LPS) receptor gene CD14, the toll-like receptor 4 gene TLR4, the gene Ce encoding the IgE heavy chain molecule and the gene FceR1 alpha coding for the alpha subunit of the IgE receptor molecule, were genotyped. Standard Fisher test was used to"@en . . "Molecular and association analysis in an endangered breed: summer dermatitis in Old Kladruber horses" . "The autochtonous Old Kladruber horse is considered as an endangered breed. Due to it's isolation and small size, occurrence of various types of diseases may represent a serious threat implicating conservation issues. Summer dermatitis occurring also in the Old Kladruber grey population is an allergic reaction to insect bites, with possible involvement of specific susceptible genotypes. According to manifested clinical signs of summer dermatitis observed over last 8 years, 73 breeding mares were classified as susceptible and resistant, respectively. A combined approach was used to screen the genome for candidate chromosome regions and/or candidate genes. 50 microsatellites and 9 single nucleotide polymorphisms (SNPs) in 5 candidate genes, the lipopolysaccharide (LPS) receptor gene CD14, the toll-like receptor 4 gene TLR4, the gene Ce encoding the IgE heavy chain molecule and the gene FceR1 alpha coding for the alpha subunit of the IgE receptor molecule, were genotyped. Standard Fisher test was used to" .