"Central European Journal of Chemistry" . "Lo\u0161\u0165\u00E1kov\u00E1, Mark\u00E9ta" . . . "6"^^ . "15310" . . "[F83BE3DED0D4]" . "7"^^ . "Separation of ketoprofen enantiomers at nanomolar concentration levels by micellar electrokinetic chromatography with on-line electrokinetic preconcentration" . "P(ED2.1.00/03.0058), P(EE2.3.20.0018), P(GAP206/12/1150), S" . . "Znaleziona, Joanna" . . "Separation of ketoprofen enantiomers at nanomolar concentration levels by micellar electrokinetic chromatography with on-line electrokinetic preconcentration" . "1895-1066" . . . "000312878400003" . "RIV/61989592:15310/13:33147305" . "104732" . "Separation of ketoprofen enantiomers at nanomolar concentration levels by micellar electrokinetic chromatography with on-line electrokinetic preconcentration"@en . "\u0160ev\u010D\u00EDk, Juraj" . "Separation of enantiomers represents an extremely important task in the field of analytical chemistry. This paper contributes to the field of the on-line preconcentration of enantiomers by developing a novel setup based on the electrokinetic accumulation of ketoprofen enantiomers on the pH boundary followed by enantioselective mobilization by a mixture of SDS, sulfated-beta-cyclodextrin (S-beta-CD), and trimethyl-beta-cyclodextrin (TM-beta-CD). Under the best conditions, where the injection electrolyte was composed of 50 mmol L-1 borate/NaOH pH 9.5 with 60% (v/v) methanol, the background electrolyte contained 50 mmol L-1 phosphate/NaOH pH 2.5, and the mobilization electrolyte consisted of 50 mmol L-1 phosphate/NaOH pH 2.5 with 4.0% (w/v) S-beta-CD, 0.5% (w/v) TM-beta-CD, and 20 mmol L-1 SDS, the determination of nanomolar concentration levels of ketoprofen enantiomers was successful by using micellar electrokinetic chromatography with a common UV detection. LODs were 2.5 nmol L-1 and 3.4 nmol L-1, which represent enhancement factors of 9921 and 8529, respectively. The method was also applied to the determination of ketoprofen enantiomers in waste water samples by using simple filtration as a clean-up step. Here, the recovery of ketoprofen enantiomers was 91% at the concentration level of 5x10(-9) mol L-1." . "10.2478/s11532-012-0177-0" . "3" . . "11" . . "Separation of ketoprofen enantiomers at nanomolar concentration levels by micellar electrokinetic chromatography with on-line electrokinetic preconcentration"@en . . . . "Petr, Jan" . "Separation of enantiomers represents an extremely important task in the field of analytical chemistry. This paper contributes to the field of the on-line preconcentration of enantiomers by developing a novel setup based on the electrokinetic accumulation of ketoprofen enantiomers on the pH boundary followed by enantioselective mobilization by a mixture of SDS, sulfated-beta-cyclodextrin (S-beta-CD), and trimethyl-beta-cyclodextrin (TM-beta-CD). Under the best conditions, where the injection electrolyte was composed of 50 mmol L-1 borate/NaOH pH 9.5 with 60% (v/v) methanol, the background electrolyte contained 50 mmol L-1 phosphate/NaOH pH 2.5, and the mobilization electrolyte consisted of 50 mmol L-1 phosphate/NaOH pH 2.5 with 4.0% (w/v) S-beta-CD, 0.5% (w/v) TM-beta-CD, and 20 mmol L-1 SDS, the determination of nanomolar concentration levels of ketoprofen enantiomers was successful by using micellar electrokinetic chromatography with a common UV detection. LODs were 2.5 nmol L-1 and 3.4 nmol L-1, which represent enhancement factors of 9921 and 8529, respectively. The method was also applied to the determination of ketoprofen enantiomers in waste water samples by using simple filtration as a clean-up step. Here, the recovery of ketoprofen enantiomers was 91% at the concentration level of 5x10(-9) mol L-1."@en . . "Ketoprofen; On-line preconcentration; Chiral separation; Capillary electrophoresis"@en . . "Knob, Radim" . "6"^^ . . . "RIV/61989592:15310/13:33147305!RIV14-GA0-15310___" . . . "Maier, V\u00EDt\u011Bzslav" . . "Ginterov\u00E1, Pavl\u00EDna" . . "Znaleziona, Joanna" . . . . "PL - Polsk\u00E1 republika" . .