"15310" . . "P(KAN115600801), P(KAN200380801), Z(MSM6198959218)" . "GB - Spojen\u00E9 kr\u00E1lovstv\u00ED Velk\u00E9 Brit\u00E1nie a Severn\u00EDho Irska" . "Bouropoulos, Nikolaos" . "Bakandritsos, Aristides" . "The preparation of magnetically guided lipid based nanoemulsions using self-emulsifying technology" . "Parker, Terry L." . . . "Mullertz, Anette" . . "RIV/61989592:15310/10:10212120!RIV11-MSM-15310___" . "5" . "This paper reports an easy and highly reproducible preparation route, using self-emulsifying technology, for an orally administered high quality magnetically responsive drug delivery system. Hydrophobic iron oxide nanoparticles of about 5 nm in diameter were prepared and incorporated into the lipid core of the produced oil droplets of a self-nanoemulsifying drug delivery system (MagC(18)/SNEDDS). The produced nanoemulsion exhibits colloidal stability at high ionic strengths and temperatures. The observed value of the saturation magnetization at 2 K is approximate to 4.1 emu g(-1). The nanoemulsion displayed the magnetic properties of a non-interacting assembly of superparamagnetic particles and a low blocking temperature. Moreover the effect of MagC(18)/SNEDDS on biological systems in vitro was investigated in rodent fibroblasts (3T3 cells). The cytotoxicity studies show that none of the formulations tested affected cell activity significantly over the 24 h incubation." . "1"^^ . . . "RIV/61989592:15310/10:10212120" . . . "Nanotechnology" . . "The preparation of magnetically guided lipid based nanoemulsions using self-emulsifying technology"@en . . . "This paper reports an easy and highly reproducible preparation route, using self-emulsifying technology, for an orally administered high quality magnetically responsive drug delivery system. Hydrophobic iron oxide nanoparticles of about 5 nm in diameter were prepared and incorporated into the lipid core of the produced oil droplets of a self-nanoemulsifying drug delivery system (MagC(18)/SNEDDS). The produced nanoemulsion exhibits colloidal stability at high ionic strengths and temperatures. The observed value of the saturation magnetization at 2 K is approximate to 4.1 emu g(-1). The nanoemulsion displayed the magnetic properties of a non-interacting assembly of superparamagnetic particles and a low blocking temperature. Moreover the effect of MagC(18)/SNEDDS on biological systems in vitro was investigated in rodent fibroblasts (3T3 cells). The cytotoxicity studies show that none of the formulations tested affected cell activity significantly over the 24 h incubation."@en . . . "particles; formulations; oxide nanoparticles; oral delivery; drug-delivery systems"@en . . "8"^^ . "281370" . "0957-4484" . "Fatouros, Dimitros G." . "Kallinteri, Paraskevi" . . . . . "000273348400004" . . "[F27C47F2E0D0]" . "The preparation of magnetically guided lipid based nanoemulsions using self-emulsifying technology" . "21" . "Favretto, Marco E." . "Zbo\u0159il, Radek" . "8"^^ . . "The preparation of magnetically guided lipid based nanoemulsions using self-emulsifying technology"@en .