"RIV/61989592:15310/09:00010752" . . . "Nov\u00E1k, Ond\u0159ej" . "Technologie v\u00FDroby [2H5]indol-3-acetyl-L-[15N]valinu pro \u00FA\u010Dely hmotov\u00E9 spektrometrie" . . "P(KAN200380801), Z(MSM6198959216)" . . "Bucht\u00EDk, Roman" . "Zatloukal, Marek" . . "Tato technologie umo\u017E\u0148uje v\u00FDrobu zcela nov\u00E9 generace intern\u00EDch standard\u016F fytohormon\u016F auxinov\u00E9ho typu, kter\u00E9 se vyu\u017E\u00EDvaj\u00ED v hmotov\u00E9 spektrometrii. C\u00EDlov\u00E9 syst\u00E9my obsahuj\u00ED deuteriem zna\u010Denou kyselinu indoly-3-octovou a 15N dus\u00EDkem zna\u010Den\u00FD valin. V\u00FDhodou t\u00E9to dosud nepopsan\u00E9 technologie je, \u017Ee p\u0159i pou\u017Eit\u00ED v analytick\u00E9 chemii je mo\u017En\u00E9 dokonale sledovat nejen metabolick\u00E9 \u0161t\u011Bpy p\u0159i studiu metabolismu auxin\u016F, ale i degradaci c\u00EDlov\u00E9 molekuly p\u0159i extrakc\u00EDch. Tato technologie je zalo\u017Eena na reakci L-[15N]valinu se sm\u011Bsn\u00FDm anhydridem kyseliny [2H5]indolyl-3-octov\u00E9 s monoethyl esterem kyseliny uhli\u010Dit\u00E9 za vzniku [2H5]indol-3-acetyl-L-[15N]valinu."@cs . "Production technology of [2H5]indol-3-acetyl-L-[15N]valine for use in mass spectrometry"@en . "15310" . . "Rol\u010D\u00EDk, Jakub" . . . . . "Technologie v\u00FDroby [2H5]indol-3-acetyl-L-[15N]valinu pro \u00FA\u010Dely hmotov\u00E9 spektrometrie" . "Strnad, Miroslav" . "6"^^ . . . "RIV/61989592:15310/09:00010752!RIV10-MSM-15310___" . "Technologie v\u00FDroby [2H5]indol-3-acetyl-L-[15N]valinu pro \u00FA\u010Dely hmotov\u00E9 spektrometrie"@cs . . "6"^^ . . . . "Tato technologie umo\u017E\u0148uje v\u00FDrobu zcela nov\u00E9 generace intern\u00EDch standard\u016F fytohormon\u016F auxinov\u00E9ho typu, kter\u00E9 se vyu\u017E\u00EDvaj\u00ED v hmotov\u00E9 spektrometrii. C\u00EDlov\u00E9 syst\u00E9my obsahuj\u00ED deuteriem zna\u010Denou kyselinu indoly-3-octovou a 15N dus\u00EDkem zna\u010Den\u00FD valin. V\u00FDhodou t\u00E9to dosud nepopsan\u00E9 technologie je, \u017Ee p\u0159i pou\u017Eit\u00ED v analytick\u00E9 chemii je mo\u017En\u00E9 dokonale sledovat nejen metabolick\u00E9 \u0161t\u011Bpy p\u0159i studiu metabolismu auxin\u016F, ale i degradaci c\u00EDlov\u00E9 molekuly p\u0159i extrakc\u00EDch. Tato technologie je zalo\u017Eena na reakci L-[15N]valinu se sm\u011Bsn\u00FDm anhydridem kyseliny [2H5]indolyl-3-octov\u00E9 s monoethyl esterem kyseliny uhli\u010Dit\u00E9 za vzniku [2H5]indol-3-acetyl-L-[15N]valinu." . . "LRR P\u0159F UP" . "[FB2996619819]" . . . ": auxin; conjugates of indolyl-3-acetic acid; mass spectrometry; analytical chemistry"@en . . . . . . "345625" . "This technology allows production of new generation of internal standard of phytohormones of the auxin type, which are usable for mass spectrometry. The target derivatives contain s deuterium labeled indolyl-3-acetic acid and 15N labelled valine. The advantage of this up to now undescribed technology is that in application in analytical chemistry is possible to follow up not only metabolite fragments but also recovery of the target compounds during extraction from different biological samples. The technology is based on reaction of L-[15N]valin with mixed anhydride of [2H5]indole-3-acetic acid and monoethyl ester of cabronic acid with formation of [2H5]indol-3-acetyl-L-[15N]valine."@en . . "Production technology of [2H5]indol-3-acetyl-L-[15N]valine for use in mass spectrometry"@en . . . "OlChemIm s.r.o., \u0160lechtitel\u016F 241/27, Olomouc, 770 10, I\u010C: 47154845, DI\u010C: CZ47154845 smlouva o poskytnut\u00ED know-how uzav\u0159ena dne 17.12.2009" . "Technologie umo\u017E\u0148uje p\u0159\u00EDpravu produktu v mno\u017E. dostate\u010Dn\u00E9m pro tr\u017En\u00ED vyu\u017Eit\u00ED. Firm\u011B Olchemim umo\u017En\u00ED prodej produktu na sv\u011Btov\u00E9m trhu a zv\u00FD\u0161\u00ED jej\u00ED konkurenceschopnost." . "indol-3-acetyl-L-valin" . "Posp\u00ED\u0161il, Tom\u00E1\u0161" . "Technologie v\u00FDroby [2H5]indol-3-acetyl-L-[15N]valinu pro \u00FA\u010Dely hmotov\u00E9 spektrometrie"@cs .