. . "Vuj\u010D\u00EDkov\u00E1, M." . "Cisatracurium vs. Rocuronium: A prospective, comparative, randomized study in adult patients under total intravenous anaesthesia." . "Cisatracurium; Rocuronium; anaesthesia."@en . "1213-8118" . . . "Jsou prezentov\u00E1ny porovn\u00E1vac\u00ED studie u dosp\u011Bl\u00FDch pacient\u016F p\u0159i \u00FApln\u00E9 vnitro\u017Eiln\u00ED anestezii"@cs . . . "2" . "468789" . "Koutn\u00E1, Ji\u0159ina" . "Cisatracurium vs. Rocuronium: A porovn\u00E1vac\u00ED studie u dosp\u011Bl\u00FDch pacient\u016F p\u0159i \u00FApln\u00E9 vnitro\u017Eiln\u00ED anestezii"@cs . . . "B\u011Blohl\u00E1vek, Radim" . "Cisatracurium vs. Rocuronium: A prospective, comparative, randomized study in adult patients under total intravenous anaesthesia."@en . . "Jan\u00E1skov\u00E1, E." . "Cisatracurium vs. Rocuronium: A prospective, comparative, randomized study in adult patients under total intravenous anaesthesia." . "[3EC4E449921A]" . "RIV/61989592:15310/06:00002878!RIV07-MZ0-15310___" . "Cisatracurium vs. Rocuronium: A prospective, comparative, randomized study in adult patients under total intravenous anaesthesia."@en . . "To compare the pharmacodynamics of cisatracurium and rocuronium-induced neuromuscular block following single dose, allowing either spontaneous or neostigmine-accelerated complete recovery. Methods: Following the ethics committee approval and informed consent, 120 patients scheduled for elective surgery under TIVA with tracheal intubation were randomized into 4 groups with different cisatracurium (CIS, 0.10 or 0.15 mg.kg-1) or rocuronium (ROC, 0.60 or 0.90 mg.kg-1) doses administered. For each patient, the onset time for 95 % depression of T1, clinical duration until 25 % recovery, recovery index (T1 from 25 to 75 %) and time from T1 25 % to TOF-ratio 0.9 were determined allowing either spontaneous or induced recovery. Results: The onset times were 277 (SD 58), 220 (46), 91 (16) and 77 (16) s for the CIS 0.10, CIS 0.15, ROC 0.60 and ROC 0.90 groups (p < 0.05), respectively, with lower variability in both ROC groups (p < 0.05). The clinical durations were 42 (7), 52 (7), 35 (11) and 52 (12) min, r"@en . "Cisatracurium vs. Rocuronium: A porovn\u00E1vac\u00ED studie u dosp\u011Bl\u00FDch pacient\u016F p\u0159i \u00FApln\u00E9 vnitro\u017Eiln\u00ED anestezii"@cs . "2"^^ . . "6"^^ . . "To compare the pharmacodynamics of cisatracurium and rocuronium-induced neuromuscular block following single dose, allowing either spontaneous or neostigmine-accelerated complete recovery. Methods: Following the ethics committee approval and informed consent, 120 patients scheduled for elective surgery under TIVA with tracheal intubation were randomized into 4 groups with different cisatracurium (CIS, 0.10 or 0.15 mg.kg-1) or rocuronium (ROC, 0.60 or 0.90 mg.kg-1) doses administered. For each patient, the onset time for 95 % depression of T1, clinical duration until 25 % recovery, recovery index (T1 from 25 to 75 %) and time from T1 25 % to TOF-ratio 0.9 were determined allowing either spontaneous or induced recovery. Results: The onset times were 277 (SD 58), 220 (46), 91 (16) and 77 (16) s for the CIS 0.10, CIS 0.15, ROC 0.60 and ROC 0.90 groups (p < 0.05), respectively, with lower variability in both ROC groups (p < 0.05). The clinical durations were 42 (7), 52 (7), 35 (11) and 52 (12) min, r" . "15310" . "P(ND7665)" . "150" . "4"^^ . . "Biomedical Papers" . "333-338" . "CZ - \u010Cesk\u00E1 republika" . "RIV/61989592:15310/06:00002878" . . . .