. "Infekce kloubn\u00ED n\u00E1hrady (d\u00E1le pouze IKN) je jednou z nej\u010Dast\u011Bj\u0161\u00EDch a nejob\u00E1van\u011Bj\u0161\u00EDch komplikac\u00ED endoprotetiky. Odhaduje se, \u017Ee k IKN m\u016F\u017Ee doj\u00EDt a\u017E u 5 % pacient\u016F s endoprot\u00E9zou ky\u010Dl\u00ED nebo kolen (28). %22Vy\u0161\u0161\u00ED incidence by m\u011Bla b\u00FDt u revizn\u00EDch operac\u00ED a u pacient\u016F se zhor\u0161enou imunitn\u00ED odpov\u011Bd\u00ED. Podstatn\u00E9 je, \u017Ee recentn\u00ED epidemiologick\u00E9 modely nazna\u010Duj\u00ED dal\u0161\u00ED n\u00E1r\u016Fst t\u011Bchto infekc\u00ED v p\u0159\u00ED\u0161t\u00EDch desetilet\u00EDch (21). Odmysl\u00EDme-li si osobn\u00ED utrpen\u00ED pacient\u016F, je z\u0159ejm\u00E9, \u017Ee v souvislosti se zm\u00EDn\u011Bn\u00FDmi progn\u00F3zami dojde k v\u00FDrazn\u00E9mu n\u00E1r\u016Fstu n\u00E1klad\u016F spojen\u00FDch s l\u00E9\u010Dbou IKN (20, 30). Z t\u011Bchto d\u016Fvod\u016F je zcela z\u00E1sadn\u00ED volba spr\u00E1vn\u00E9 preventivn\u00ED strategie, kter\u00E1 by minimalizovala riziko vzniku IKN. Z pohledu prevence jsou nejefektivn\u011Bj\u0161\u00ED postupy, kter\u00E9 ovliv\u0148uj\u00ED periopera\u010Dn\u00ED a \u010Dasn\u00E9 poopera\u010Dn\u00ED obdob\u00ED, kdy se tvo\u0159\u00ED biofilm."@cs . . "\u0160v\u00E1bov\u00E1, Maria" . "80" . . "Kol\u00E1\u0159, Milan" . "1" . "RIV/61989592:15110/13:33143643" . . . "8"^^ . . "Infekce kloubn\u00ED n\u00E1hrady (d\u00E1le pouze IKN) je jednou z nej\u010Dast\u011Bj\u0161\u00EDch a nejob\u00E1van\u011Bj\u0161\u00EDch komplikac\u00ED endoprotetiky. Odhaduje se, \u017Ee k IKN m\u016F\u017Ee doj\u00EDt a\u017E u 5 % pacient\u016F s endoprot\u00E9zou ky\u010Dl\u00ED nebo kolen (28). %22Vy\u0161\u0161\u00ED incidence by m\u011Bla b\u00FDt u revizn\u00EDch operac\u00ED a u pacient\u016F se zhor\u0161enou imunitn\u00ED odpov\u011Bd\u00ED. Podstatn\u00E9 je, \u017Ee recentn\u00ED epidemiologick\u00E9 modely nazna\u010Duj\u00ED dal\u0161\u00ED n\u00E1r\u016Fst t\u011Bchto infekc\u00ED v p\u0159\u00ED\u0161t\u00EDch desetilet\u00EDch (21). Odmysl\u00EDme-li si osobn\u00ED utrpen\u00ED pacient\u016F, je z\u0159ejm\u00E9, \u017Ee v souvislosti se zm\u00EDn\u011Bn\u00FDmi progn\u00F3zami dojde k v\u00FDrazn\u00E9mu n\u00E1r\u016Fstu n\u00E1klad\u016F spojen\u00FDch s l\u00E9\u010Dbou IKN (20, 30). Z t\u011Bchto d\u016Fvod\u016F je zcela z\u00E1sadn\u00ED volba spr\u00E1vn\u00E9 preventivn\u00ED strategie, kter\u00E1 by minimalizovala riziko vzniku IKN. Z pohledu prevence jsou nejefektivn\u011Bj\u0161\u00ED postupy, kter\u00E9 ovliv\u0148uj\u00ED periopera\u010Dn\u00ED a \u010Dasn\u00E9 poopera\u010Dn\u00ED obdob\u00ED, kdy se tvo\u0159\u00ED biofilm." . "\u0160iller, Michal" . . "Gallo, Ji\u0159\u00ED" . . "Prosthetic joint infection is a feared complication in total hip arthroplasty. The use of antibiotic-impregnated bone cement is the important part of preventive and therapeutic strategies. At present a number of commercial bone cements are available and support of their use by the results of experimental trials and clinical studies has varied. In relation to this issue we studied essential microbiological and pharmacological characteristics of VancogenX in comparison with gentamicin-loaded bone cement used conventionally."@en . . "Mikrobiologick\u00E9 a farmakologick\u00E9 vlastnosti kostn\u00EDho cementu VancogenX"@cs . "Acta chirurgiae orthopaedicae et traumatologiae \u010Cechoslovaca" . "CZ - \u010Cesk\u00E1 republika" . "Mikrobiologick\u00E9 a farmakologick\u00E9 vlastnosti kostn\u00EDho cementu VancogenX" . . . . "[5D688F917B94]" . "RIV/61989592:15110/13:33143643!RIV14-MZ0-15110___" . "Mikrobiologick\u00E9 a farmakologick\u00E9 vlastnosti kostn\u00EDho cementu VancogenX"@cs . . . "Microbial and Pharmacological Characteristics of VancogenX"@en . . "88313" . . "Microbial and Pharmacological Characteristics of VancogenX"@en . . . "6"^^ . "P(NT11049), S" . . . "Lo\u0161\u0165\u00E1k, Ji\u0159\u00ED" . . "15110" . . . "Bogdanov\u00E1, Kate\u0159ina" . "0001-5415" . . "VancogenX; dilution, prevention; gentamicin, vancomycin; prosthetic joint infection; vacuum mixed; antibiotic-loaded PMMA"@en . "Mikrobiologick\u00E9 a farmakologick\u00E9 vlastnosti kostn\u00EDho cementu VancogenX" . "3"^^ .