"RIV/61989592:15110/10:33117968" . "\u0160koloud\u00EDk, David" . "US - Spojen\u00E9 st\u00E1ty americk\u00E9" . "Langov\u00E1, Kate\u0159ina" . "Changes in hemocoagulation in acute stroke patients after one-hour sono-thrombolysis using a diagnostic probe." . "Ultrasound in Medicine and Biology" . . . . "Roubec, Martin" . . "7" . "8"^^ . "Ka\u0148ovsk\u00FD, Petr" . "Bardo\u0148, Petr" . . "The aim was to monitor the changes in hemocoagulation parameters in acute ischemic stroke (AIS) patients after sono-thrombolysis of the occluded middle cerebral artery using a duplex transcranial probe with 2.0-MHz frequency in Doppler mode. Sixteen AIS patients indicated for intravenous thrombolysis (IVT) (8 males; mean age 68.3 +/- 7.1 y) and 16 AIS patients contraindicated for IVT (11 males; mean age 67.9 +/- 7.9 y) were randomized for sono-thrombolysis (8 + 8 patients) or standard treatment (control group) (8 + 8 patients). The significant decrease of plasminogen activator inhibitor-1, plasminogen and alpha-2-antiplasmin activity by a mean of 60, 32 and 24%, respectively, and the increase of tissue plasminogen activator by a mean of 56% was found after sono-thrombolysis when compared with control group (p { 0.0125); these changes were more evident in patients treated with a combination of sono-thrombolysis and IVT (79, 38, 50 and 82%, respectively) than in patients treated by sono-thrombolysis alone (34, 13, 17 and 30%, respectively)."@en . . . . "5"^^ . . . "Changes in hemocoagulation in acute stroke patients after one-hour sono-thrombolysis using a diagnostic probe." . "P(NR9487), V" . "36" . "11"^^ . . . "250294" . "15110" . "\u0160a\u0148\u00E1k, Daniel" . "000279066000002" . . "sono-thrombolysis; acute stroke; hemocoagulation"@en . "0301-5629" . . . "Zapletal, Ond\u0159ej" . "RIV/61989592:15110/10:33117968!RIV13-MZ0-15110___" . . "[70AF2ADDE11A]" . "Herzig, Roman" . "Fadrn\u00E1, T\u00E1\u0148a" . "Blatn\u00FD, J." . . "Changes in hemocoagulation in acute stroke patients after one-hour sono-thrombolysis using a diagnostic probe."@en . "Bar, Michal" . . . "Changes in hemocoagulation in acute stroke patients after one-hour sono-thrombolysis using a diagnostic probe."@en . "The aim was to monitor the changes in hemocoagulation parameters in acute ischemic stroke (AIS) patients after sono-thrombolysis of the occluded middle cerebral artery using a duplex transcranial probe with 2.0-MHz frequency in Doppler mode. Sixteen AIS patients indicated for intravenous thrombolysis (IVT) (8 males; mean age 68.3 +/- 7.1 y) and 16 AIS patients contraindicated for IVT (11 males; mean age 67.9 +/- 7.9 y) were randomized for sono-thrombolysis (8 + 8 patients) or standard treatment (control group) (8 + 8 patients). The significant decrease of plasminogen activator inhibitor-1, plasminogen and alpha-2-antiplasmin activity by a mean of 60, 32 and 24%, respectively, and the increase of tissue plasminogen activator by a mean of 56% was found after sono-thrombolysis when compared with control group (p { 0.0125); these changes were more evident in patients treated with a combination of sono-thrombolysis and IVT (79, 38, 50 and 82%, respectively) than in patients treated by sono-thrombolysis alone (34, 13, 17 and 30%, respectively)." . . "10.1016/j.ultrasmedbio.2010.04.010" .