. . "4"^^ . . "RIV/61989592:15110/10:10213434" . "Lenalidomid v l\u00E9\u010Db\u011B refraktern\u00EDho mnoho\u010Detn\u00E9ho myelomu"@cs . . . . "1801-1209" . "6" . "268268" . "The paper presents a case report of a patient with multiple myeloma. The patient was refractory to high-dosed chemotherapy as well as novel biological treatment (bortezomib, thalidomide). Within the next course we introduced a treatment regimen with the use of lenalidomide, which lead to a significant therapeutical effect with the achievement of remission of the disease, and the treatment could be later on fortified by autologous stem cell transplantation. We conclude that lenalidomide is a potent biological drug, convenient for patiens with refraktory multiple myeloma."@en . . "Pika, Tom\u00E1\u0161" . "Ba\u010Dovsk\u00FD, Jaroslav" . "15110" . "Lenalidomid v l\u00E9\u010Db\u011B refraktern\u00EDho mnoho\u010Detn\u00E9ho myelomu" . . . . "\u0160\u010Dudla, Vlastimil" . . "cyclophosphamide; thalidomide; bortezomibe; lenalidomide"@en . "V" . . "Lenalidomide in the therapy of refractory multiple myeloma"@en . "Lenalidomid v l\u00E9\u010Db\u011B refraktern\u00EDho mnoho\u010Detn\u00E9ho myelomu"@cs . . . "Mina\u0159\u00EDk, Ji\u0159\u00ED" . "Lenalidomid v l\u00E9\u010Db\u011B refraktern\u00EDho mnoho\u010Detn\u00E9ho myelomu" . . "P\u0159edlo\u017Een\u00E1 pr\u00E1ce hodnot\u00ED p\u0159\u00EDpad pacienta s mnoho\u010Detn\u00FDm myelomem, u n\u011Bj\u017E ani vysokod\u00E1vkovan\u00E1 chemoterapie v\u010Detn\u011B nov\u00FDch biologick\u00FDch l\u00E9k\u016F (bortezomib, thalidomid) nevedla k v\u00FDznamn\u011Bj\u0161\u00ED redukci n\u00E1dorov\u00E9 masy. V dal\u0161\u00EDm pr\u016Fb\u011Bhu byl proto do terapie za\u0159azen lenalidomid, kter\u00FD vedl v v\u00FDznamn\u00E9mu l\u00E9\u010Debn\u00E9mu efektu s dosa\u017Een\u00EDm remise onemocn\u011Bn\u00ED a umo\u017En\u011Bn\u00EDm autologn\u00ED transplantace kostn\u00ED d\u0159en\u011B. Lze zhodnotit, \u017Ee lenalidomid je velmi potentn\u00EDm biologick\u00FDm l\u00E9kem vhodn\u00FDm pro nemocn\u00E9 s refraktern\u00EDm mnoho\u010Detn\u00FDm myelomem."@cs . "RIV/61989592:15110/10:10213434!RIV11-MSM-15110___" . . "Lenalidomide in the therapy of refractory multiple myeloma"@en . "CZ - \u010Cesk\u00E1 republika" . "4"^^ . "P\u0159edlo\u017Een\u00E1 pr\u00E1ce hodnot\u00ED p\u0159\u00EDpad pacienta s mnoho\u010Detn\u00FDm myelomem, u n\u011Bj\u017E ani vysokod\u00E1vkovan\u00E1 chemoterapie v\u010Detn\u011B nov\u00FDch biologick\u00FDch l\u00E9k\u016F (bortezomib, thalidomid) nevedla k v\u00FDznamn\u011Bj\u0161\u00ED redukci n\u00E1dorov\u00E9 masy. V dal\u0161\u00EDm pr\u016Fb\u011Bhu byl proto do terapie za\u0159azen lenalidomid, kter\u00FD vedl v v\u00FDznamn\u00E9mu l\u00E9\u010Debn\u00E9mu efektu s dosa\u017Een\u00EDm remise onemocn\u011Bn\u00ED a umo\u017En\u011Bn\u00EDm autologn\u00ED transplantace kostn\u00ED d\u0159en\u011B. Lze zhodnotit, \u017Ee lenalidomid je velmi potentn\u00EDm biologick\u00FDm l\u00E9kem vhodn\u00FDm pro nemocn\u00E9 s refraktern\u00EDm mnoho\u010Detn\u00FDm myelomem." . "[7059BFC1035F]" . . "Farmakoterapie : diagetologie - alergologie - pneumologie - revmatologie" . "2"^^ . . "2" .