"268142" . . . . . "L\u00E9\u010Dba obsedantn\u011B-kompulz\u00EDvn\u00ED poruchy"@cs . . "RIV/61989592:15110/10:10212110" . "Pra\u0161ko Pavlov, J\u00E1n" . "7"^^ . "Mlad\u00E1 fronta Dnes" . . . "1"^^ . . "L\u00E9\u010Dba obsedantn\u011B-kompulz\u00EDvn\u00ED poruchy" . "V" . "Obsessive compulsive disorder and its treatment"@en . "1"^^ . "12" . . . "CZ - \u010Cesk\u00E1 republika" . "Obsessive compulsive disorder is common psychiatric disorders. Newer treatments, specifically cognitive behavioral therapy and serotonergic agents, have helped significantly in symptom amelioration. Cognitive-behavioral therapy demonstrated long term efficacy in most of the patients with obsessive compulsive disorders in many research studies. It is estimated that the symptoms of approximately 60% of patients respond to a trial with antidepressants. Consequently, a significant number of patients are left with residual symptoms and disability. Some patients who do not respond to an SRI trial may respond upon addition of a low dose of antipsychotics. Augmentation with other several agents such as lithium, buspirone, pindolol has been tried with variable success in some patients. Chronic refractory OCD causing documented persistent, severe disability is sometimes treated palliatively with neurosurgical procedures such as anterior cingulotomy or anterior capsulotomy."@en . "[173330A1F743]" . "RIV/61989592:15110/10:10212110!RIV11-MSM-15110___" . "L\u00E9\u010Dba obsedantn\u011B-kompulz\u00EDvn\u00ED poruchy"@cs . "1210-1168" . "Obsedantn\u011B-kompulz\u00EDvn\u00ED porucha pat\u0159\u00ED mezi \u010Dast\u00E9 psychiatrick\u00E9 probl\u00E9my. Nov\u00E9 p\u0159\u00EDstupy v l\u00E9\u010Db\u011B, obzvl\u00E1\u0161t\u011B kognitivn\u011B- behavior\u00E1ln\u00ED terapie a serotonergn\u00ED l\u00E1tky, mohou v\u00FDrazn\u011B pomoci v jej\u00ED l\u00E9\u010Db\u011B. Kognitivn\u011B-behavior\u00E1ln\u00ED terapie uk\u00E1zala dlouhodobou \u00FA\u010Dinnost u v\u011Bt\u0161iny pacient\u016F v \u0159ad\u011B studi\u00ED. Kolem 60 % pacient\u016F reaguje na pod\u00E1v\u00E1n\u00ED antidepresiv. P\u0159esto \u0159ada pacient\u016F z\u016Fst\u00E1v\u00E1 l\u00E9\u010Dbou neovlivn\u011Bna nebo s rezidu\u00E1ln\u00ED symptomatologi\u00ED. N\u011Bkte\u0159\u00ED pacienti, kte\u0159\u00ED nereaguj\u00ED na samotn\u00E1 antidepresiva, mohou m\u00EDt u\u017Eitek z p\u0159id\u00E1n\u00ED mal\u00FDch d\u00E1vek antipsychotik. Augmentace dal\u0161\u00EDmi l\u00E9ky, jako jsou lithium, buspiron, pindolol, byla \u00FAsp\u011B\u0161n\u011B pou\u017Eita u n\u011Bkter\u00FDch pacient\u016F. Chronick\u00E1 rezistentn\u00ED obsedantn\u011B-kompulz\u00EDvn\u00ED porucha, kter\u00E1 vede k v\u00E1\u017En\u00E9mu distresu a handicap\u016Fm, m\u016F\u017Ee b\u00FDt tak\u00E9 l\u00E9\u010Dena neurochirurgick\u00FDm z\u00E1sahem." . "Obsessive compulsive disorder and its treatment"@en . . . . . . "L\u00E9\u010Dba obsedantn\u011B-kompulz\u00EDvn\u00ED poruchy" . "cognitive behavioral therapy.; antipsychotics; antidepressants; obsessive compulsive disorders"@en . "Obsedantn\u011B-kompulz\u00EDvn\u00ED porucha pat\u0159\u00ED mezi \u010Dast\u00E9 psychiatrick\u00E9 probl\u00E9my. Nov\u00E9 p\u0159\u00EDstupy v l\u00E9\u010Db\u011B, obzvl\u00E1\u0161t\u011B kognitivn\u011B- behavior\u00E1ln\u00ED terapie a serotonergn\u00ED l\u00E1tky, mohou v\u00FDrazn\u011B pomoci v jej\u00ED l\u00E9\u010Db\u011B. Kognitivn\u011B-behavior\u00E1ln\u00ED terapie uk\u00E1zala dlouhodobou \u00FA\u010Dinnost u v\u011Bt\u0161iny pacient\u016F v \u0159ad\u011B studi\u00ED. Kolem 60 % pacient\u016F reaguje na pod\u00E1v\u00E1n\u00ED antidepresiv. P\u0159esto \u0159ada pacient\u016F z\u016Fst\u00E1v\u00E1 l\u00E9\u010Dbou neovlivn\u011Bna nebo s rezidu\u00E1ln\u00ED symptomatologi\u00ED. N\u011Bkte\u0159\u00ED pacienti, kte\u0159\u00ED nereaguj\u00ED na samotn\u00E1 antidepresiva, mohou m\u00EDt u\u017Eitek z p\u0159id\u00E1n\u00ED mal\u00FDch d\u00E1vek antipsychotik. Augmentace dal\u0161\u00EDmi l\u00E9ky, jako jsou lithium, buspiron, pindolol, byla \u00FAsp\u011B\u0161n\u011B pou\u017Eita u n\u011Bkter\u00FDch pacient\u016F. Chronick\u00E1 rezistentn\u00ED obsedantn\u011B-kompulz\u00EDvn\u00ED porucha, kter\u00E1 vede k v\u00E1\u017En\u00E9mu distresu a handicap\u016Fm, m\u016F\u017Ee b\u00FDt tak\u00E9 l\u00E9\u010Dena neurochirurgick\u00FDm z\u00E1sahem."@cs . "15110" . "7" .