"Kal\u00E1bov\u00E1, Hana" . "29" . "P(NR9096), S" . "1"^^ . "Melichar, Bohuslav" . "15110" . "Serum Homocysteine, Cholesterol, Retinol, alpha-Tocopherol, Glycosylated Hemoglobin and Inflammatory Response during Therapy with Bevacizumab, Oxaliplatin, 5-Fluorouracil and Leucovorin" . "metastatic colorectal carcinoma; homocysteine; Bevacizumab"@en . . "Kr\u010Dmov\u00E1, L." . "Background: Targeted agents present with a new spectrum of side-effects, including toxicities that negatively impact the risk of atherosclerosis. The aim of the present study was to evaluate the effect of the combination of targeted therapy and chemotherapy on serum homocysteine and other laboratory parameters of cardiovascular risk in patients with metastatic colorectal carcinoma. Patients and Methods: Thirty-one patients with metastatic colorectal carcinoma treated with the combination of bevacizumab, oxaliplatin, 5-fluorouracil and leucovorin were studied before and during the therapy. Results: Serum homocysteine decreased significantly throughout the course of treatment." . "340898" . "Serum Homocysteine, Cholesterol, Retinol, alpha-Tocopherol, Glycosylated Hemoglobin and Inflammatory Response during Therapy with Bevacizumab, Oxaliplatin, 5-Fluorouracil and Leucovorin"@en . "[E6A098D03376]" . "Serum Homocysteine, Cholesterol, Retinol, alpha-Tocopherol, Glycosylated Hemoglobin and Inflammatory Response during Therapy with Bevacizumab, Oxaliplatin, 5-Fluorouracil and Leucovorin"@en . . "Mal\u00ED\u0159ov\u00E1, E." . "RIV/61989592:15110/09:10223890" . . "Background: Targeted agents present with a new spectrum of side-effects, including toxicities that negatively impact the risk of atherosclerosis. The aim of the present study was to evaluate the effect of the combination of targeted therapy and chemotherapy on serum homocysteine and other laboratory parameters of cardiovascular risk in patients with metastatic colorectal carcinoma. Patients and Methods: Thirty-one patients with metastatic colorectal carcinoma treated with the combination of bevacizumab, oxaliplatin, 5-fluorouracil and leucovorin were studied before and during the therapy. Results: Serum homocysteine decreased significantly throughout the course of treatment."@en . . . . "0250-7005" . . . "RIV/61989592:15110/09:10223890!RIV12-MSM-15110___" . . . . "Serum Homocysteine, Cholesterol, Retinol, alpha-Tocopherol, Glycosylated Hemoglobin and Inflammatory Response during Therapy with Bevacizumab, Oxaliplatin, 5-Fluorouracil and Leucovorin" . "8"^^ . "GR - \u0158eck\u00E1 republika" . "ANTICANCER RESEARCH" . . "Ka\u0161parov\u00E1, M." . . "9"^^ . . . . "11" .