. "S, Z(MSM6198959216)" . . "Hajd\u00FAch, Mari\u00E1n" . "\u010Desk\u00FD institut pro akreditaci" . "Examination of oncogene mutations and polymorphisms by DNA sequencing"@en . . "Dr\u00E1bek, Ji\u0159\u00ED" . "Vy\u0161et\u0159en\u00ED mutac\u00ED a polymorfism\u016F onkogen\u016F sekvenov\u00E1n\u00EDm DNA"@cs . "Srovnal, Josef" . . "rutinn\u00ED vy\u0161et\u0159ov\u00E1n\u00ED pacient\u016F" . . . "DNA sequencing allows reading of a particular stretch of DNA. By comparing the obtained sequences with well-known sequence of the DNA molecule, we find single nucleotide substitution (point mutation) in the chain, which may be responsible for the changed activity of the resulting protein (eg EGFR, KRAS)."@en . "RIV/61989592:15110/09:00010983!RIV10-MSM-15110___" . "3"^^ . "15110" . "Vy\u0161et\u0159en\u00ED mutac\u00ED a polymorfism\u016F onkogen\u016F sekvenov\u00E1n\u00EDm DNA"@cs . . . . "Vy\u0161et\u0159en\u00ED mutac\u00ED a polymorfism\u016F onkogen\u016F sekvenov\u00E1n\u00EDm DNA" . . . "350420" . "Sekvenace DNA umo\u017E\u0148uje p\u0159e\u010Dten\u00ED ur\u010Dit\u00E9ho \u00FAseku DNA. Porovn\u00E1n\u00EDm takto z\u00EDskan\u00E9 sekvence s obecn\u011B zn\u00E1mou sekvenc\u00ED dan\u00E9 molekuly DNA vyhled\u00E1me jednonukleotidov\u00E9 z\u00E1m\u011Bny (bodov\u00E9 mutace) v \u0159et\u011Bzci, kter\u00E9 mohou b\u00FDt zodpov\u011Bdn\u00E9 za zv\u00FD\u0161enou aktivitu v\u00FDsledn\u00E9ho proteinu."@cs . . "3"^^ . "Examination of oncogene mutations and polymorphisms by DNA sequencing"@en . . . "427/2009" . . "C_SOP_08" . . . . "sequencing; gene; point mutation; activating mutation; DNA"@en . "Sekvenace DNA umo\u017E\u0148uje p\u0159e\u010Dten\u00ED ur\u010Dit\u00E9ho \u00FAseku DNA. Porovn\u00E1n\u00EDm takto z\u00EDskan\u00E9 sekvence s obecn\u011B zn\u00E1mou sekvenc\u00ED dan\u00E9 molekuly DNA vyhled\u00E1me jednonukleotidov\u00E9 z\u00E1m\u011Bny (bodov\u00E9 mutace) v \u0159et\u011Bzci, kter\u00E9 mohou b\u00FDt zodpov\u011Bdn\u00E9 za zv\u00FD\u0161enou aktivitu v\u00FDsledn\u00E9ho proteinu." . "2009-07-13+02:00"^^ . . "[E25C30E7A750]" . "L\u00E9ka\u0159sk\u00E1 fakulta Univerzity Palack\u00E9ho v Olomouci" . . "Vy\u0161et\u0159en\u00ED mutac\u00ED a polymorfism\u016F onkogen\u016F sekvenov\u00E1n\u00EDm DNA" . "RIV/61989592:15110/09:00010983" .