"Ulrichov\u00E1, Jitka" . "333492" . . "Olomouc" . . "Clinical study about effect of silymarin and selen on the healthy men a patients after radical prostatectomy"@en . . "Z(MSM6198959216)" . "Objectives: The aim of our study was to evaluate the chemopreventive effect of silymarin, selenium (silymarin / sylimarinov\u00FD Complex 190 mg, selenium (selenomethionine) 25 mg, 10 mg phytosterols) to the prostate. Conclusion: Our results confirm the six-month use of food supplements Selenium Silymarin-PSA decline and improve urinary parameters in study I, study I and II have been shown to improve the subjective perception of the patient urinate (IPSS, QoL)."@en . "Pilotn\u00ED klinick\u00E9 studie \u00FA\u010Dinku silymarinu a selenu na zdrav\u00FDch dobrovoln\u00EDc\u00EDch a pacientech po radik\u00E1ln\u00ED prostatektomii"@cs . "RIV/61989592:15110/09:00009665" . . "\u0160im\u00E1nek, Vil\u00EDm" . . "Pilotn\u00ED klinick\u00E9 studie \u00FA\u010Dinku silymarinu a selenu na zdrav\u00FDch dobrovoln\u00EDc\u00EDch a pacientech po radik\u00E1ln\u00ED prostatektomii" . . . . "Vost\u00E1lov\u00E1, Jitka" . . . "\u0160tudent, Vladim\u00EDr" . . "K\u0159en, V." . . "Univerzita Palack\u00E9ho" . "C\u00EDle: C\u00EDlem pr\u00E1ce bylo vyhodnotit \u00FA\u010Dinek p\u0159\u00EDpravku Silymarin-selen (silymarin 190 mg, selen (selenomethionin) 25 mg, fytosteroly 10 mg) pod\u00E1van\u00E9ho 180 dn\u00ED na prostatu a doln\u00ED cesty mo\u010Dov\u00E9. Metody: Dvojit\u011B slep\u00E9, placebem kontrolovan\u00E9 studie prob\u00EDhaly od 10/2007 do 12/2008 na dvou souborech pacient\u016F. Do studie I bylo za\u0159azeno 56 zdrav\u00FDch mu\u017E\u016F (vstupn\u00ED kriteria: PSA < 2,5, negativn\u00ED DRE, 40-70 let); do studie II 47 mu\u017E\u016F po radik\u00E1ln\u00ED prostatektomii (vstupn\u00ED kriterium: 2 m\u011Bs\u00EDce po RRP bez adjuvatn\u00ED l\u00E9\u010Dby). V\u0161ichni \u00FA\u010Dastn\u00EDci u\u017E\u00EDvali 180 dn\u00ED 3x denn\u011B dopln\u011Bk stravy Silymarin-selen nebo placebo. Byli kontrolov\u00E1ni p\u0159i za\u0159azen\u00ED do studie, jej\u00ED polovin\u011B a v den ukon\u010Den\u00ED (den 0, 90 a 180). P\u0159i kontrol\u00E1ch bylo provedeno: klinick\u00E9 vy\u0161et\u0159en\u00ED, BMI, IPSS, IIEF-5; laboratorn\u00ED parametry: PSA, TST, selen, CRP, hematologie, klinick\u00E1 biochemie (bezpe\u010Dnostn\u00ED laborato\u0159, lipidov\u00FD profil, jatern\u00ED funkce), parametry oxida\u010Dn\u00EDho stresu. Ve studii I tak\u00E9 urodynamick\u00E9 parametry: pr\u016Fm\u011Brn\u00FD pr\u016Ftok - Qpr, maxim\u00E1ln\u00ED pr\u016Ftok - Q" . . . . . "8"^^ . "Vrbkov\u00E1, Jana" . "Clinical study about effect of silymarin and selen on the healthy men a patients after radical prostatectomy"@en . "Pilotn\u00ED klinick\u00E9 studie \u00FA\u010Dinku silymarinu a selenu na zdrav\u00FDch dobrovoln\u00EDc\u00EDch a pacientech po radik\u00E1ln\u00ED prostatektomii"@cs . . "Stejskal, David" . . "www.urol.cz" . "C\u00EDle: C\u00EDlem pr\u00E1ce bylo vyhodnotit \u00FA\u010Dinek p\u0159\u00EDpravku Silymarin-selen (silymarin 190 mg, selen (selenomethionin) 25 mg, fytosteroly 10 mg) pod\u00E1van\u00E9ho 180 dn\u00ED na prostatu a doln\u00ED cesty mo\u010Dov\u00E9. Metody: Dvojit\u011B slep\u00E9, placebem kontrolovan\u00E9 studie prob\u00EDhaly od 10/2007 do 12/2008 na dvou souborech pacient\u016F. Do studie I bylo za\u0159azeno 56 zdrav\u00FDch mu\u017E\u016F (vstupn\u00ED kriteria: PSA < 2,5, negativn\u00ED DRE, 40-70 let); do studie II 47 mu\u017E\u016F po radik\u00E1ln\u00ED prostatektomii (vstupn\u00ED kriterium: 2 m\u011Bs\u00EDce po RRP bez adjuvatn\u00ED l\u00E9\u010Dby). V\u0161ichni \u00FA\u010Dastn\u00EDci u\u017E\u00EDvali 180 dn\u00ED 3x denn\u011B dopln\u011Bk stravy Silymarin-selen nebo placebo. Byli kontrolov\u00E1ni p\u0159i za\u0159azen\u00ED do studie, jej\u00ED polovin\u011B a v den ukon\u010Den\u00ED (den 0, 90 a 180). P\u0159i kontrol\u00E1ch bylo provedeno: klinick\u00E9 vy\u0161et\u0159en\u00ED, BMI, IPSS, IIEF-5; laboratorn\u00ED parametry: PSA, TST, selen, CRP, hematologie, klinick\u00E1 biochemie (bezpe\u010Dnostn\u00ED laborato\u0159, lipidov\u00FD profil, jatern\u00ED funkce), parametry oxida\u010Dn\u00EDho stresu. Ve studii I tak\u00E9 urodynamick\u00E9 parametry: pr\u016Fm\u011Brn\u00FD pr\u016Ftok - Qpr, maxim\u00E1ln\u00ED pr\u016Ftok - Q"@cs . "[5EC4DFF0947F]" . . "silymarin; selen; prostate"@en . "Pilotn\u00ED klinick\u00E9 studie \u00FA\u010Dinku silymarinu a selenu na zdrav\u00FDch dobrovoln\u00EDc\u00EDch a pacientech po radik\u00E1ln\u00ED prostatektomii" . . "15110" . "Vidl\u00E1\u0159, Ale\u0161" . . "6"^^ . "RIV/61989592:15110/09:00009665!RIV10-MSM-15110___" .