"7"^^ . . . "Efficacy of sentinel lymph node biopsy in patients with malignant melanoma"@en . "Introduction: Sentinellymph node (SLN) biopsy and subsequent clinical assessment show different results in some patients with malignant melanoma (MM). The incidence of a false negative SLN is less than 2% in a case of comparison of SLN status with a histological finding in the remaining lymph nodes in the Iymphatic basin. However, the incidence of lymphatic metastases in the adjacent lymphatic basins varies in patients with negative SLN from4% to 27% duringthe follow-up (Mariani G et a1.JNucl Med 2002; 43: 811-827). The aim of the study was to evaluate this parameter in a large group ofpatients. Methods: 170 consecutive patients with MM underwent SLN biopsy and subsequently were followed at the Dept. of Oncology. 2 patients were excluded from the study due to the local recurrence with secondary lymph node metastasis, therefore a total of 168 patients were studied. Loca1ization of MMs: 91 trunk, 67 extremities, 10 head and neck. TNM classification: 48 pTI, 65 pT2, 32 pT3, 19 pT4, 4 pTiS. T" . "Spolehlivost biopsie sentinelov\u00FDch uzlin u malign\u00EDho melanomu"@cs . "Efficacy of sentinel lymph node biopsy in patients with malignant melanoma"@en . "Spolehlivost biopsie sentinelov\u00FDch uzlin u malign\u00EDho melanomu"@cs . . "Hir\u0148\u00E1k, J." . "Nuklearmedizin" . "4"^^ . "Efficacy of sentinel lymph node biopsy in patients with malignant melanoma" . "6" . "Efficacy of sentinel lymph node biopsy in patients with malignant melanoma" . "Bajgar, Robert" . "RIV/61989592:15110/07:00004356" . . . . . "C\u00EDlem studie bylo pomoc\u00ED klinick\u00E9ho sledov\u00E1n\u00ED zhodnotit spolehlivost biopsie sentinelov\u00FDch lymfatick\u00FDch uzlin (SLU) p\u0159i detekci uzlinov\u00FDch metast\u00E1z u pacient\u016F (pac.) s malign\u00EDm melanomem (MM). Celkem byla SLU biopsie provedena u 170 pac. s MM. 2 pacienti s lok\u00E1ln\u00ED recidivou MM byli vylou\u010Deni ze studie pro mo\u017Enost vzniku uzlinov\u00E9 metast\u00E1zy na z\u00E1klad\u011B recidivy. Celkem hodnoceno 168 osob. Lokalizace MM: 91 trup, 67 kon\u010Detiny, 10 hlava a krk. TNM: 48 pT1, 65 pT2, 32 pT3, 19 pT4, 4 pTiS. St\u0159edn\u00ED doba sledov\u00E1n\u00ED 2,6 roku (0,5-5,7, medi\u00E1n 2,4 roku). SLU nalezeny u v\u0161ech pac. ? 100% \u00FAsp\u011B\u0161nost detekce SLU. Metast\u00E1zy v SLU detekov\u00E1ny u 25/168 pac. (1/48 pT1, 6/65 pT2, 8/32 pT3, 10/19 pT4). N\u00E1sledn\u00E9 klinick\u00E9 sledov\u00E1n\u00ED zjistilo lymfatick\u00E9 metast\u00E1zy u dal\u0161\u00EDch 4 pac.(1 pT2, 1pT3, 2 pT4), z toho ve 3 p\u0159\u00EDpadech \u0161lo o MM na dist\u00E1ln\u00EDch parti\u00EDch doln\u00EDch kon\u010Detin. Senzitivita SLU biopsie 86 %, negativn\u00ED prediktivn\u00ED hodnota 97 %. P\u0159i hodnocen\u00ED bez 6 pacient\u016F s MM na noze: senzitivita 96,1%, NPV 99,3%. U 3 pac. zji\u0161t\u011Bny vz"@cs . "0029-5566" . . "DE - Spolkov\u00E1 republika N\u011Bmecko" . . "S" . . "[5252C6C1071B]" . "1"^^ . "419331" . . "RIV/61989592:15110/07:00004356!RIV08-MSM-15110___" . . . "46" . "15110" . . "Koranda, Pavel" . "Introduction: Sentinellymph node (SLN) biopsy and subsequent clinical assessment show different results in some patients with malignant melanoma (MM). The incidence of a false negative SLN is less than 2% in a case of comparison of SLN status with a histological finding in the remaining lymph nodes in the Iymphatic basin. However, the incidence of lymphatic metastases in the adjacent lymphatic basins varies in patients with negative SLN from4% to 27% duringthe follow-up (Mariani G et a1.JNucl Med 2002; 43: 811-827). The aim of the study was to evaluate this parameter in a large group ofpatients. Methods: 170 consecutive patients with MM underwent SLN biopsy and subsequently were followed at the Dept. of Oncology. 2 patients were excluded from the study due to the local recurrence with secondary lymph node metastasis, therefore a total of 168 patients were studied. Loca1ization of MMs: 91 trunk, 67 extremities, 10 head and neck. TNM classification: 48 pTI, 65 pT2, 32 pT3, 19 pT4, 4 pTiS. T"@en . "sentinel lymph node biopsy; malignant melanoma"@en . . "Bene\u0161, Petr" . . "Myslive\u010Dek, Miroslav" . "168" . "Molitor, M." . "Kam\u00EDnek, Milan" .