"498910" . . "RIV/61989592:15110/06:00003944!RIV08-MZ0-15110___" . . . "Sentinel lymph node biopsy: a new lperspective in head and neck mucosal melanoma?" . "Biopsie sentinelov\u00E9 uzliny: nov\u00E1 perspektiva u slizni\u010Dn\u00EDch melanom\u016F hlavy a krku?"@cs . "423-427" . "Sentinel lymph node biopsy in patients with head and neck mucosal melanomas has not been performed so far Therefore, this Metod as a staging tool was tested in a pilot study. In two consecutive patients, a lymphoscintigraphy, elective neck dissection with radio-guided sentinel lymph node identification, and resection of the primary were performed. The histopathological status of the sentinel lymph node was compared with the lymphadenectomy specimen and with the clinical course. Patient no. 1, in whom both the sentinel lymph node and the lymphadenectomy specimen were found to be free of tumour, is well and with no evidence of disease, the follow-up interval being 19 months. Patient no. 2, with the sentinel lymph node and remaining lymphatic basin being positive and negative, respectively, developed hematogenous dissemination 3 months after the primary treatment, and he was started on paliative chemotherapy. In mucosal melanoma, the prognostic significance of clinical nodal status is controversial, resu" . "5"^^ . "Biopsie sentinelov\u00E9 uzliny: nov\u00E1 perspektiva u slizni\u010Dn\u00EDch melanom\u016F hlavy a krku?"@cs . . "[83824A755588]" . "Biopsie sentinelov\u00FDch uzlin u pacient\u016F se slizni\u010Dn\u00EDm melanonem hlavy a krku dosud nebyla provedena. Proto byla tato metoda testov\u00E1na v pilotn\u00ED studii jako st\u00E1\u017Eovac\u00ED n\u00E1stroj. U pacient\u016F byla provedena lymfoscintigrafie, elektivn\u00ED kr\u010Dn\u00ED disekce s radionavigovanou identifikac\u00ED sentinelov\u00E9 uzliny a resekce prim\u00E1rn\u00EDho tumoru. Histopatologick\u00FD stav sentinelov\u00E9 uzliny byl porovn\u00E1n s odstran\u011Bn\u00FDmi kr\u010Dn\u00EDmi uzlinami a s klinick\u00FDm pr\u016Fb\u011Bhem. Pacient \u010D. 1, u n\u011Bho\u017E sentinelov\u00E1 uzlina i kr\u010Dn\u00ED uzliny byly negativn\u00ED, \u017Eije 19 m\u011Bs\u00EDc\u016F bez zn\u00E1mek onemocn\u011Bn\u00ED. U pacienta \u010D. 2 s pozitivn\u00ED sentinelovou uzlinou a negativn\u00ED blokovou disekc\u00ED se objevila hematogenn\u00ED diseminace t\u0159i m\u011Bs\u00EDce po operaci a byla mu nasazena paliativn\u00ED chemoterapie. U slizni\u010Dn\u00EDch melanom\u016F je prognostick\u00FD v\u00FDznam histopatologick\u00E9ho stavu uzlin sporn\u00FD, z \u010Deho\u017E vypl\u00FDv\u00E1 chyb\u011Bn\u00ED ofici\u00E1ln\u00ED TM klasifikace i terapeutick\u00FDch standard\u016F. P\u0159\u00EDtomnost mikroskopick\u00E9ho metastatick\u00E9ho lo\u017Eiska v sentinelov\u00E9 uzlin\u011B byla spojena s \u010Dasnou hematogenn\u00ED diseminac\u00ED. Biopsie senti"@cs . "P(NK7738)" . . . . "16" . "Sentinel lymph node biopsy: a new lperspective in head and neck mucosal melanoma?"@en . "Koranda, Pavel" . "Bene\u0161, P." . . "sentinel lymph node; mucosal melanoma; head; neck"@en . . "Sentinel lymph node biopsy: a new lperspective in head and neck mucosal melanoma?" . . . "3"^^ . "Melanoma Res." . . "2"^^ . . "Sentinel lymph node biopsy in patients with head and neck mucosal melanomas has not been performed so far Therefore, this Metod as a staging tool was tested in a pilot study. In two consecutive patients, a lymphoscintigraphy, elective neck dissection with radio-guided sentinel lymph node identification, and resection of the primary were performed. The histopathological status of the sentinel lymph node was compared with the lymphadenectomy specimen and with the clinical course. Patient no. 1, in whom both the sentinel lymph node and the lymphadenectomy specimen were found to be free of tumour, is well and with no evidence of disease, the follow-up interval being 19 months. Patient no. 2, with the sentinel lymph node and remaining lymphatic basin being positive and negative, respectively, developed hematogenous dissemination 3 months after the primary treatment, and he was started on paliative chemotherapy. In mucosal melanoma, the prognostic significance of clinical nodal status is controversial, resu"@en . . . "US - Spojen\u00E9 st\u00E1ty americk\u00E9" . "15110" . "Sentinel lymph node biopsy: a new lperspective in head and neck mucosal melanoma?"@en . "0960-8931" . . "St\u00E1rek, Ivo" . . "5" . "RIV/61989592:15110/06:00003944" .