"Endometr\u00E1ln\u00ED exprese estrogen senzitivn\u00EDch gen\u016F MMP-26 a TIMP-4 je zm\u011Bn\u011Bna substitu\u010Dn\u00EDm protokolem bez downregulace u IVF pacientek"@cs . "4"^^ . "[780CF6DC8D45]" . "12" . . "Pilka, Radovan" . . "Estradiol/progesteronov\u00E1 substituce vyvol\u00E1v\u00E1 dramatick\u00E9 zm\u011Bny v expresi estrogen senzitivn\u00EDch gen\u016F MMP-26 a TIMP-4, kter\u00E9 mohou nep\u0159\u00EDzniv\u011B ovlivnit v\u00FDsledek IVF."@cs . "P(NH6611)" . "RIV/61989592:15110/06:00003923" . "Endometr\u00E1ln\u00ED exprese estrogen senzitivn\u00EDch gen\u016F MMP-26 a TIMP-4 je zm\u011Bn\u011Bna substitu\u010Dn\u00EDm protokolem bez downregulace u IVF pacientek"@cs . "Lichnovsk\u00FD, V\u00E1clav" . . "15110" . "Casslen, Bertil" . "Endometrial expression of the estrogen-sensitive genes MMP-26 and TIMP-4 is altered by a substitution protocol without down-regulation in IVF patiens" . . "474108" . . "RIV/61989592:15110/06:00003923!RIV08-MZ0-15110___" . . "Eriksson, Per" . "Oborn\u00E1, Ivana" . "Fingerov\u00E1, Helena" . . . "Endometrial expression of the estrogen-sensitive genes MMP-26 and TIMP-4 is altered by a substitution protocol without down-regulation in IVF patiens"@en . . . "11"^^ . . "1355-4786" . . "21" . "3146-3156" . "estrogen; implantation; mRNA; progesterone receptor; regulation"@en . "Endometrial expression of the estrogen-sensitive genes MMP-26 and TIMP-4 is altered by a substitution protocol without down-regulation in IVF patiens"@en . "GB - Spojen\u00E9 kr\u00E1lovstv\u00ED Velk\u00E9 Brit\u00E1nie a Severn\u00EDho Irska" . "Havelka, Pavel" . . . "8"^^ . . "BACKGROUND: The aim of this study was to analyse the effects of an estradiol (E2)?progesterone substitution protocol on the endometrial expression of estrogen-sensitive genes during the peri-implantation period. METHODS: Peripheral blood and endometrial biopsies were obtained from 13 infertile women both in a natural cycle (NC), on days 5 and 7 after ovulation (NC5, NC7), and in an artificial (substituted) cycle (AC), on days 5 and 7 of progesterone addition (AC5, AC7). Estrogen receptor-\u03B1 (ER \u03B1) and progesterone receptor (PR) were assayed by immunohistochemistry. Matrix metalloproteinase-26 (MMP-26) mRNA and tissue inhibitor of metalloproteinase-4 (TIMP-4) mRNA were semiquantitatively assessed in tissue sections using in situ hybridization (ISH) and quantified in tissue extracts using real-time PCR. RESULTS: Levels of both E2 and progesterone were higher in the peripheral blood in AC than in NC. Also on day AC5, expressions of ER \u03B1, PR and MMP-26 mRNA (focally) were increased in the e"@en . . . "Human Reproduction Update" . "Endometrial expression of the estrogen-sensitive genes MMP-26 and TIMP-4 is altered by a substitution protocol without down-regulation in IVF patiens" . . . . "BACKGROUND: The aim of this study was to analyse the effects of an estradiol (E2)?progesterone substitution protocol on the endometrial expression of estrogen-sensitive genes during the peri-implantation period. METHODS: Peripheral blood and endometrial biopsies were obtained from 13 infertile women both in a natural cycle (NC), on days 5 and 7 after ovulation (NC5, NC7), and in an artificial (substituted) cycle (AC), on days 5 and 7 of progesterone addition (AC5, AC7). Estrogen receptor-\u03B1 (ER \u03B1) and progesterone receptor (PR) were assayed by immunohistochemistry. Matrix metalloproteinase-26 (MMP-26) mRNA and tissue inhibitor of metalloproteinase-4 (TIMP-4) mRNA were semiquantitatively assessed in tissue sections using in situ hybridization (ISH) and quantified in tissue extracts using real-time PCR. RESULTS: Levels of both E2 and progesterone were higher in the peripheral blood in AC than in NC. Also on day AC5, expressions of ER \u03B1, PR and MMP-26 mRNA (focally) were increased in the e" . "Hansson, Stefan" .