"The Tumor Suppressor Gene PTEN Plays a Role in Cell Cycle Regulation and Apoptosis in Prostate Cancer Cell Lines"@en . . . . "N\u00E1dorov\u00FD supresorov\u00FD gen PTEN hraje \u00FAlohu v regulaci bun\u011B\u010Dn\u00E9ho cyklu a apopt\u00F3zy v prostatick\u00FDch n\u00E1dorov\u00FDch lini\u00ED."@cs . "Phosphatase and tension homology deleted on chromosome ten (PTEN) is a tumor suppressor gene with protein and lipid phosphatase activity frequently altered in several types of human cancers. Herein, we demonstrate the effect of transfected wild type (wt) PTEN and its mutants (mt) L57W, H123Y, G129R that have lost lipid and protein phosphatase activity; and G129E characterized by loss of only lipid phosphatase activity, during the cell cycle and on apoptosis." . "N\u00E1dorov\u00FD supresor PTEN blokuje bun\u011B\u010Dn\u00FD cyklus na p\u0159echodu f\u00E1ze G1-S u prostatick\u00FDch n\u00E1dorov\u00FDch lini\u00ED. Pro funkci PTEN v regulaci bun\u011B\u010Dn\u00E9ho cyklu je nutn\u00E1 jeho fosfat\u00E1zov\u00E1 aktivita. PTEN hraje d\u016Fle\u017Eitou \u00FAlohu v negativn\u00ED regulaci PI3K/Akt dr\u00E1hy."@cs . . "PTEN/MMAC; phosphatase; cell cycle"@en . . "The Tumor Suppressor Gene PTEN Plays a Role in Cell Cycle Regulation and Apoptosis in Prostate Cancer Cell Lines" . "Hormonal Carcinogenesis - Proceeding of the 4th International Symposium" . "P(NC6779), Z(MSM 151100001)" . "Guldberg, Per" . "15110" . . "\u0160v\u00E1chov\u00E1, Michaela" . . . . "The Tumor Suppressor Gene PTEN Plays a Role in Cell Cycle Regulation and Apoptosis in Prostate Cancer Cell Lines"@en . "7"^^ . "7"^^ . . . "7"^^ . . "5"^^ . "Knillov\u00E1, Jana" . "Springer-Verlag" . "Pimrov\u00E1, Eva" . . . "590966" . "\u0158ih\u00E1kov\u00E1, Petra" . . "Phosphatase and tension homology deleted on chromosome ten (PTEN) is a tumor suppressor gene with protein and lipid phosphatase activity frequently altered in several types of human cancers. Herein, we demonstrate the effect of transfected wild type (wt) PTEN and its mutants (mt) L57W, H123Y, G129R that have lost lipid and protein phosphatase activity; and G129E characterized by loss of only lipid phosphatase activity, during the cell cycle and on apoptosis."@en . . . "Kol\u00E1\u0159, Zden\u011Bk" . "Hlobilkov\u00E1, Alice" . "0-387-23783-6" . "N\u00E1dorov\u00FD supresorov\u00FD gen PTEN hraje \u00FAlohu v regulaci bun\u011B\u010Dn\u00E9ho cyklu a apopt\u00F3zy v prostatick\u00FDch n\u00E1dorov\u00FDch lini\u00ED."@cs . "The Tumor Suppressor Gene PTEN Plays a Role in Cell Cycle Regulation and Apoptosis in Prostate Cancer Cell Lines" . . "RIV/61989592:15110/04:00006054" . . . "RIV/61989592:15110/04:00006054!RIV09-MZ0-15110___" . . "[278017B521C1]" .