"Carboxylic acid is the main product of roscovitine biotransformation in mice in vivo. Comparison with bohemine"@en . "RIV/61989592:15110/03:00007296!RIV09-MSM-15110___" . "Vesel\u00FD, Jaroslav" . . "Carboxylic acid is the main product of roscovitine biotransformation in mice in vivo. Comparison with bohemine" . . . "\u00DA\u010Delem pr\u00E1ce bylo zkoum\u00E1n\u00ED clearance selektivn\u00EDho inhibitoru Cdk roscovitinu a s rovn\u00E1n\u00ED s boheminem u my\u0161\u00ED in vivo."@cs . . . "Riegrov\u00E1, Dagmar" . "Chmela, Zden\u011Bk" . "\u010Cervenkov\u00E1, Kate\u0159ina" . "Carboxylic acid is the main product of roscovitine biotransformation in mice in vivo. Comparison with bohemine"@en . "carboxylic acid; roscovitine; biotransformation; mice; bohemine"@en . . "Rypka, Miroslav" . "Kyselina karboxylov\u00E1 je hlavn\u00EDm produktem biotransformace roscovitinu u my\u0161\u00ED in vivo. Srovn\u00E1n\u00ED s boheminem"@cs . . . "Monduzzi Editore" . "Bologna, Italy" . "4"^^ . . "P(OC B17.20), Z(MSM 151100001)" . "[480FE6367548]" . . "15110" . . "Kyselina karboxylov\u00E1 je hlavn\u00EDm produktem biotransformace roscovitinu u my\u0161\u00ED in vivo. Srovn\u00E1n\u00ED s boheminem"@cs . "88-323-3141-1" . . . "The purpose of the present study was to investigate clearance of selective cyclin-dependent kinase inhibitor roscovitine and to compare it with that of bohemine in mice in vivo. Clearence of roscovitine in mice was about four times slower than that of bohemine. Due to potential effects on the saturation of enzyme systems involved in the clearance, the in vivo study should be extended using high doses of the administered compounds." . . "600361" . . . . "RIV/61989592:15110/03:00007296" . "Carboxylic acid is the main product of roscovitine biotransformation in mice in vivo. Comparison with bohemine" . . . "The purpose of the present study was to investigate clearance of selective cyclin-dependent kinase inhibitor roscovitine and to compare it with that of bohemine in mice in vivo. Clearence of roscovitine in mice was about four times slower than that of bohemine. Due to potential effects on the saturation of enzyme systems involved in the clearance, the in vivo study should be extended using high doses of the administered compounds."@en . . "6"^^ . "Lemr, Karel" . . "5"^^ . "Cytochromes P450, Biochemistry, Biophysics and Drug Metabolism. 13th International Conference on Cytochromes P450" . . .