"Modriansk\u00FD, Martin" . "High performance liquid chromatography and capillary electrophoresis determination of sanquinarine in biological matrices"@en . "1615-9306" . "P(GP303/01/P085), Z(MSM 151100003)" . . "\u0160ev\u010D\u00EDk, Juraj" . . "Bedn\u00E1\u0159, Petr" . . "HPLC and CE methods were employed to determine the quaternary benzo[c]phenanthridine alkaloid sanguinarine in biological matrices (rat hepatocytes, human gingival fibroblasts, feed, porcine faeces, body fluids and tissues). Both methods are suitable for analysing submicromolar quantities of sanguinarine in biological materials. The HPLC method is more sensitive than CE because it uses fluorescence detection."@en . "HPLC a kapil\u00E1rn\u011B elektroforetick\u00E9 stanoven\u00ED sanguinarinu v biologick\u00FDch matric\u00EDch"@cs . "8" . "High performance liquid chromatography and capillary electrophoresis determination of sanquinarine in biological matrices" . "High performance liquid chromatography and capillary electrophoresis determination of sanquinarine in biological matrices" . . "Kosina, Pavel" . . "HPLC and CE methods were employed to determine the quaternary benzo[c]phenanthridine alkaloid sanguinarine in biological matrices (rat hepatocytes, human gingival fibroblasts, feed, porcine faeces, body fluids and tissues). Both methods are suitable for analysing submicromolar quantities of sanguinarine in biological materials. The HPLC method is more sensitive than CE because it uses fluorescence detection." . . . "DE - Spolkov\u00E1 republika N\u011Bmecko" . . . "RIV/61989592:15110/03:00006969!RIV09-MSM-15110___" . "Journal of Separation Science" . . "Gavenda, Ale\u0161" . "Walterov\u00E1, Daniela" . "Ulrichov\u00E1, Jitka" . . "HPLC a CE metody byly pou\u017Eity pro stanoven\u00ED kvart\u00E9rn\u00EDho benzo[c]fenanthridinov\u00E9ho alkaloidu sanguinarinu v biologick\u00FDch matric\u00EDch (potkan\u00ED hepatocyty, lidsk\u00E9 gingiv\u00E1ln\u00ED fibroblasty, krmivo, prase\u010D\u00ED feaces, t\u011Bln\u00EDch tekutin\u00E1ch a tk\u00E1n\u00EDch). HPLC byla prov\u00E1d\u011Bna na C18 kolon\u011B gradientovou eluc\u00ED s vyu\u017Eit\u00EDm ionp\u00E1rov\u00E9ho \u010Dinidla (kyseliny 1-heptansulfonov\u00E9) v kysel\u00E9m prost\u0159ed\u00ED. Detek\u010Dn\u00ED limit p\u0159i fluorimetrick\u00E9 detekci (327/577 nm) byl 3 nmol.l-1. CE anal\u00FDzy byly prov\u00E1d\u011Bny ve fosf\u00E1tov\u00E9m-Na pufru (50 mM), pH 2,5 s 150 mM SDS pro prekoncentraci a sweeping efekt. Tato technika umo\u017Enila nast\u0159\u00EDknut\u00ED cel\u00E9ho objemu kapil\u00E1ry se vzorkem obsahuj\u00EDc\u00EDm sanguinarin. Detek\u010Dn\u00ED limit pro UV detekci byl 12 nM. Ob\u011B metody jsou vhodn\u00E9 pro anal\u00FDzy submikromol\u00E1rn\u00EDch koncentrac\u00ED sanguinarinu v biologick\u00FDch materi\u00E1lech. HPLC metoda je citliv\u011Bj\u0161\u00ED d\u00EDky pou\u017Eit\u00ED fluorimetrick\u00E9 detekce."@cs . . . . "[EF46D8AB1A11]" . . "15110" . "High performance liquid chromatography and capillary electrophoresis determination of sanquinarine in biological matrices"@en . "26" . . "Bart\u00E1k, Petr" . . "608800" . . . "7"^^ . "RIV/61989592:15110/03:00006969" . . "HPLC a kapil\u00E1rn\u011B elektroforetick\u00E9 stanoven\u00ED sanguinarinu v biologick\u00FDch matric\u00EDch"@cs . "sanguinarin; HPLC; kapil\u00E1rn\u00ED elektrofor\u00E9za; biologick\u00E9 matrice"@en . . . . . "7"^^ . "8"^^ .