"S" . . . "666878" . "RIV/61988987:17110/02:A1000VRW" . "Gumulec, Jarom\u00EDr" . . . . "0042-773X" . . "2"^^ . "The objective of the investigation is evaluation of therapeutic results and the development of the prognosis of patients with multiple myeloma (MM) as a result of consecutive changes of therapeutic procedures in patients of central and northern Moravia in the course of the last 40 years. Methods and results: Conclusion: From the submitted analysis ensured that during the period form 1959 - 2000 in patients with mutiple myeloma in central and northern Moravia as a result of the application of modern methods of chemotheraphy and supporting treatment a significant improvements of results of conventional treatment occurred with a more than 5 fold prolongation of so far assessable median values of survival (8 - 44 months) and long-term 10-year survival of almost one sixth of the patients. The real asset of %22HD%22 theraphy with transplantation of ASCT will be revealed by analyses made after a longer time interval."@en . "CZ - \u010Cesk\u00E1 republika" . "antineoplastic agen"@en . . "Therapeutic results and changes in prognosis in patients with multiple myeloma in central and northern Moravia over the past 40 years" . "Vnit\u0159n\u00ED l\u00E9ka\u0159stv\u00ED" . . "11"^^ . "Mart\u00EDnek, Arno\u0161t" . "Therapeutic results and changes in prognosis in patients with multiple myeloma in central and northern Moravia over the past 40 years"@en . "[976B715E4292]" . "8" . . . "48" . "The objective of the investigation is evaluation of therapeutic results and the development of the prognosis of patients with multiple myeloma (MM) as a result of consecutive changes of therapeutic procedures in patients of central and northern Moravia in the course of the last 40 years. Methods and results: Conclusion: From the submitted analysis ensured that during the period form 1959 - 2000 in patients with mutiple myeloma in central and northern Moravia as a result of the application of modern methods of chemotheraphy and supporting treatment a significant improvements of results of conventional treatment occurred with a more than 5 fold prolongation of so far assessable median values of survival (8 - 44 months) and long-term 10-year survival of almost one sixth of the patients. The real asset of %22HD%22 theraphy with transplantation of ASCT will be revealed by analyses made after a longer time interval." . "17110" . . "Therapeutic results and changes in prognosis in patients with multiple myeloma in central and northern Moravia over the past 40 years" . "RIV/61988987:17110/02:A1000VRW!RIV10-MSM-17110___" . . "2"^^ . "Therapeutic results and changes in prognosis in patients with multiple myeloma in central and northern Moravia over the past 40 years"@en . .