. . "Novel pyrazolo[4,3-D]pyrimidines, processes for their preparation and methods for therapy"@en . . . . . "P(GA301/08/1649), P(GA522/09/1576)" . "[07A1E6EA1DC4]" . . "2010-06-22+02:00"^^ . "RIV/61389030:_____/10:00352738!RIV11-GA0-61389030" . . . "Nouveaux pyrazolo[4,3-D]pyrimidines, procedes pour leur preparation et methodes" . . . . . . "Lenobel, Ren\u00E9" . . . . "5"^^ . . "Kry\u0161tof, Vladim\u00EDr" . "Havl\u00ED\u010Dek, Libor" . . "novel pyrazolo[4,3-D]pyrimidines; process; preparation; method; therapy"@en . "Ottawa" . . . "5"^^ . . . "CA2480409" . "Nouveaux pyrazolo[4,3-D]pyrimidines, procedes pour leur preparation et methodes" . "Canadian Intellectual Property Office http://brevets-patents.ic.gc.ca/opic-cipo/cpd/eng/patent/2480409/summary.html?type=number_search" . "Moravcov\u00E1, Daniela" . . "Novel pyrazolo[4,3-D]pyrimidines, processes for their preparation and methods for therapy"@en . "275179" . "\u00DAstav experiment\u00E1ln\u00ED botaniky AV \u010CR, v. v. i., Univerzita Palack\u00E9ho v Olomouci" . . "L'invention concerne \u00E0 3 -, 5 -,7-pyrazolo trisubstitu\u00E9s (4,3-d) pyrimidines repr\u00E9sent\u00E9 par la formule g\u00E9n\u00E9rale (I), et alkyle, cycloalkyle, cycloh\u00E9t\u00E9roalkyle, cycloalkyle, alkyle, aryle ou alkylaryle, R5 est halog\u00E8ne,-NHNH2,-NHOH, NHCONH2, guanylo (NH-C (NH) NH2) \u00E9ventuellement substitu\u00E9 C1-C6 alkyle, alc\u00E9nyle, alcynyle, cycloalkyle en C3-C15, Rf (cycloalkyle en C3-C15), un h\u00E9t\u00E9rocycle, h\u00E9t\u00E9roalkyle, aryle , h\u00E9t\u00E9roaryle, arylalkyle, cycloh\u00E9t\u00E9roalkyle, alkyle cycloh\u00E9t\u00E9roalkyle, h\u00E9t\u00E9roarylalkyle groupe etc.Cette invention concerne de nouveaux pyrazolo (4,3-d) pyrimidine et leur utilisation dans les services publics appropri\u00E9s, en particulier les m\u00E9thodes diagnostiques et th\u00E9rapeutiques. Plus pr\u00E9cis\u00E9ment, la pr\u00E9sente invention concerne \u00E9galement l'utilisation du 3,5,7-pyrazolo trisubstitu\u00E9s (4,3-d) pyrimidines ou un sel pharmaceutiquement acceptable de celui-ci en combinaison avec des cytostatiques dans la pr\u00E9paration d'un m\u00E9dicament pour traiter le cancer." . . "RIV/61389030:_____/10:00352738" . . "Strnad, Miroslav" . . "The invention relates to 3-,5-,7-trisubstituted pyrazolo(4,3-d)pyrimidines represented by the general formula (I), and substituted alkyl, cycloalkyl, cycloheteroalkyl, cycloalkyl, alkyl, aryl or alkylaryl group, R5 is halogen, -NHNH2, -NHOH, NHCONH2, guanylo (NH-C(NH)NH2) an optionally substituted C1-C6 alkyl, alkenyl, alkinyl, C3-C15 cycloalkyl, Rf (C3-C15 cycloalkyl), heterocycle, heteroalkyl, aryl, heteroaryl, arylalkyl, cycloheteroalkyl, cycloheteroalkyl alkyl, heteroarylalkyl group etc.This invention relates to new pyrazolo(4,3-d)pyrimidine derivatives and to their use in suitable utilities, especially diagnostic and therapeutic methods. More specifically, the present invention also relates to the use of 3,5,7-trisubstituted pyrazolo(4,3-d)pyrimidines or a pharmaceutically acceptable salt thereof in combination with cytostatics in the preparation of a medicament for treating cancer."@en . .