"The European Patent Office (EPO) http://v3.espacenet.com/publicationDetails/originalDocument?FT=D&date=20100825&DB=EPODOC&locale=en_EP&CC=EP&NR=1348707B1&KC=B1" . "Mnichov" . "Pyrazolo[4,3-D]pyrimidines, processes for their preparation and methods for therapy" . . . "Pyrazolo[4,3-D]pyrimidines; processes; preparation; methods; therapy"@en . "\u00DAstav experiment\u00E1ln\u00ED botaniky AV \u010CR, v. v. i., Univerzita Palack\u00E9ho v Olomouci" . . "RIV/61389030:_____/10:00352737" . "EP1348707" . . "5"^^ . . "[2F951CDB2F27]" . . "283528" . "5"^^ . "P(GA301/08/1649), P(GA522/09/1576)" . . . . "Pyrazolo[4,3-D]pyrimidines, processes for their preparation and methods for therapy" . . "Pyrazolo[4,3-D]pyrimidines, processes for their preparation and methods for therapy"@en . "The invention relates to new pyrazolo (4,3-d)pyrimidine derivatives and to their use in suitable utilities, especially diagnostic and therapeutic methods. It is an object of this invention to provide anticancer, anti-inflammatory, antiviral, antineurodegenerative, neurodepressive and immunosuppressive compounds having improved selectivity and efficiency index, i. E. that are less toxic yet more efficacious tha analogues known heretofore. It is an object of this invention to provide 3,5,7-trisubstituted pyrazolo(4,3-d)pyrimidines, which inhibit the cdks, cell proliferation, and/or induce apoptosis. A further object of the invention is to provide pharmaceutical composition, which comprises a 3,5,7-ftrisubstituted pyrazolo(4,3-d)pyrimidine and a pharmaceutically acceptable carrier."@en . "2010-08-25+02:00"^^ . . . . "Moravcov\u00E1, Daniela" . "Pyrazolo[4,3-D]pyrimidines, processes for their preparation and methods for therapy"@en . . . "Lenobel, Ren\u00E9" . . . . . . "RIV/61389030:_____/10:00352737!RIV11-GA0-61389030" . . . "Kry\u0161tof, Vladim\u00EDr" . . . . . "Havl\u00ED\u010Dek, Libor" . "Strnad, Miroslav" . . . "The invention relates to new pyrazolo (4,3-d)pyrimidine derivatives and to their use in suitable utilities, especially diagnostic and therapeutic methods. It is an object of this invention to provide anticancer, anti-inflammatory, antiviral, antineurodegenerative, neurodepressive and immunosuppressive compounds having improved selectivity and efficiency index, i. E. that are less toxic yet more efficacious tha analogues known heretofore. It is an object of this invention to provide 3,5,7-trisubstituted pyrazolo(4,3-d)pyrimidines, which inhibit the cdks, cell proliferation, and/or induce apoptosis. A further object of the invention is to provide pharmaceutical composition, which comprises a 3,5,7-ftrisubstituted pyrazolo(4,3-d)pyrimidine and a pharmaceutically acceptable carrier." . .