. . . "Distribution of polyethylene wear particles and bone fragments in periprosthetic tissue around total hip joint replacements"@en . "Distribution of polyethylene wear particles and bone fragments in periprosthetic tissue around total hip joint replacements"@en . . "\u0160louf, Miroslav" . . "Pokorn\u00FD, D." . "Zolotarevova, E." . "Ultra-high molecular weight polyethylene (UHMWPE) wear particles play a significant role in failures of total joint replacements (TJRs). In this work, we investigated the distribution of these wear particles in periprosthetic tissues obtained from nine revisions of hip TJR. All periprosthetic tissues were combined and mechanically separated into granuloma tissue (containing hard granules visible to the naked eye) and surrounding tissue (without visible granules). Of the total amount of polyethylene particles in the whole granuloma tissue, 72% of particles in the size range 0.1\u201310 um and 68% of those larger than 10 um were found in granules. Therefore, the formation of granules significantly lowers the effective amount of wear particles available for interaction with reactive cells and seems to be a natural defense mechanism."@en . "I, P(2B06096), Z(AV0Z40500505)" . "254748" . "6"^^ . "GB - Spojen\u00E9 kr\u00E1lovstv\u00ED Velk\u00E9 Brit\u00E1nie a Severn\u00EDho Irska" . "Gallo, J." . "joint replacement; polyethylene; wear particles distribution"@en . "9" . "Ultra-high molecular weight polyethylene (UHMWPE) wear particles play a significant role in failures of total joint replacements (TJRs). In this work, we investigated the distribution of these wear particles in periprosthetic tissues obtained from nine revisions of hip TJR. All periprosthetic tissues were combined and mechanically separated into granuloma tissue (containing hard granules visible to the naked eye) and surrounding tissue (without visible granules). Of the total amount of polyethylene particles in the whole granuloma tissue, 72% of particles in the size range 0.1\u201310 um and 68% of those larger than 10 um were found in granules. Therefore, the formation of granules significantly lowers the effective amount of wear particles available for interaction with reactive cells and seems to be a natural defense mechanism." . . "6" . "Entlicher, G." . . . . "Pavlova, Ewa" . "Sosna, A." . . "8"^^ . "Vesel\u00FD, F." . "RIV/61389013:_____/10:00347024!RIV11-MSM-61389013" . . . . "Pavlova, Ewa" . . "[0EDC022D64BC]" . . "Distribution of polyethylene wear particles and bone fragments in periprosthetic tissue around total hip joint replacements" . . "000281318400026" . . "2"^^ . "Acta Biomaterialia" . . "RIV/61389013:_____/10:00347024" . "1742-7061" . "Distribution of polyethylene wear particles and bone fragments in periprosthetic tissue around total hip joint replacements" .