"Aachen" . "978-3-540-85225-4" . "ultrahigh molecular weight polyethylene; nanometer size wear debris; morphology"@en . "Ultra-high molecular weight polyethylene (UHMWPE) has been used as a bearing material in total joint replacements (TJR) for more than forty years. Friction between polymer and metallic/ceramics components of TJR leads to generation of UHMWPE wear particles, which are released from the joint space and cause complex inflammatory reactions leading to aseptic bone loosening. The wear particles have sizes range from submicron to several-millimeters. It is generally accepted that particles below 10 .mu.m exhibit the highest biological activity. The existence of nano-sized particles was proof in a multidirectional pin on plate wear simulator. Our work brings the first proof that nano-sized wear particles are produced also in vivo." . . . "RIV/61389013:_____/08:00312258" . . . "Nanometer size wear debris generated from ultra high molecular weight polyethylene in vivo"@en . "Ultra-high molecular weight polyethylene (UHMWPE) has been used as a bearing material in total joint replacements (TJR) for more than forty years. Friction between polymer and metallic/ceramics components of TJR leads to generation of UHMWPE wear particles, which are released from the joint space and cause complex inflammatory reactions leading to aseptic bone loosening. The wear particles have sizes range from submicron to several-millimeters. It is generally accepted that particles below 10 .mu.m exhibit the highest biological activity. The existence of nano-sized particles was proof in a multidirectional pin on plate wear simulator. Our work brings the first proof that nano-sized wear particles are produced also in vivo."@en . "Entlicher, G." . "Po v\u00EDce ne\u017E \u010Dty\u0159icet let je ultra vysokomolekul\u00E1rn\u00ED polyethylen pou\u017E\u00EDv\u00E1n jako nosn\u00FD materi\u00E1l u tot\u00E1ln\u00EDch ky\u010Deln\u00EDch n\u00E1hrad. T\u0159en\u00ED mezi polymerem a kovovou \u010Di keramickou \u010D\u00E1st\u00ED n\u00E1hrady vede ke vzniku ot\u011Brov\u00FDch \u010D\u00E1stic, kter\u00E9 jsou uvol\u0148ov\u00E1ny z prostoru kloubu a jsou p\u0159\u00ED\u010Dinou z\u00E1n\u011Btliv\u00FDch reakc\u00ED, kter\u00E9 mohou v\u00E9st a\u017E k aseptick\u00E9mu selh\u00E1n\u00ED kosti. Ot\u011Brov\u00E9 \u010D\u00E1stice maj\u00ED velikosti od submikron\u016F a\u017E po n\u011Bkolik milimetr\u016F. Je obecn\u011B p\u0159ij\u00EDm\u00E1no, \u017Ee \u010D\u00E1stice pod 10 .mu.m vykazuj\u00ED nejvy\u0161\u0161\u00ED biologickou aktivitu. Vznik ot\u011Bru ve velikosti n\u011Bkolika nanometr\u016F byl prok\u00E1z\u00E1n v ot\u011Brov\u00E9m simul\u00E1toru. Na\u0161e pr\u00E1ce poprv\u00E9 prok\u00E1zala, \u017Ee je produkov\u00E1n take in vivo."@cs . "Sosna, A." . . "2"^^ . . "Springer Verlag Berlin Heidelberg" . "[99E73EA50D83]" . "Proceedings of 14th European Microscopy Congress EMC 2008" . . "8"^^ . "Nanometrov\u00E9 \u010D\u00E1stice vznikaj\u00EDc\u00ED z ultra vysokomolekul\u00E1rn\u00EDho polyethylenu in vivo"@cs . . . "2008-09-01+02:00"^^ . "Gallo, J." . . . "Dybal, Ji\u0159\u00ED" . "381603" . "Zolotarevova, E." . "Pokorn\u00FD, D." . . "3"^^ . . "RIV/61389013:_____/08:00312258!RIV09-AV0-61389013" . "Nanometer size wear debris generated from ultra high molecular weight polyethylene in vivo" . . . "Nanometer size wear debris generated from ultra high molecular weight polyethylene in vivo"@en . "Nanometrov\u00E9 \u010D\u00E1stice vznikaj\u00EDc\u00ED z ultra vysokomolekul\u00E1rn\u00EDho polyethylenu in vivo"@cs . . . "Nanometer size wear debris generated from ultra high molecular weight polyethylene in vivo" . "\u0160louf, Miroslav" . . . "Lap\u010D\u00EDkov\u00E1, Monika" . "Berlin" . . "P(2B06096), Z(AV0Z40500505)" .