. "Yeast multicellular colonies possess several traits that are absent from individual yeasts. These include the ability to synchronize colony population development and adapt its metabolism to different environmental changes, such as nutrient depletion. This, together with cell diversification to cell variants with distinct metabolic and other properties, contributes to the main goal of the colony population: to achieve longevity. In this respect, a benefit to individual cells is subordinated to the benefit to the whole population, exhibiting a kind of altruistic behaviour. For example, some colony cells located at particular positions undergo regulated cell dying and provide components to other cells located in more propitious areas. The enhancement of techniques that enable the in vivo investigation of three-dimensional spatiotemporal colony development can lead to new discoveries on metabolic differentiation and regulation in the near future"@en . "Aging and longevity of yeast colony populations: metabolic adaptation and differentiation"@en . "RIV/61388971:_____/11:00370714!RIV12-AV0-61388971" . "P(GA204/08/0718), P(LC531), Z(AV0Z50200510), Z(MSM0021620858)" . "-" . . . "Aging and longevity of yeast colony populations: metabolic adaptation and differentiation" . "GB - Spojen\u00E9 kr\u00E1lovstv\u00ED Velk\u00E9 Brit\u00E1nie a Severn\u00EDho Irska" . "V\u00E1chov\u00E1, Libu\u0161e" . "Aging and longevity of yeast colony populations: metabolic adaptation and differentiation" . "[56355B8C4A16]" . . "000295745200063" . . . "adaptation and longevity; ammonia signalling; quorum sensing"@en . "10.1042/BST0391471" . . . . . . . . . . "184874" . "5"^^ . "RIV/61388971:_____/11:00370714" . "Aging and longevity of yeast colony populations: metabolic adaptation and differentiation"@en . "Palkov\u00E1, Z." . "2"^^ . . . "Yeast multicellular colonies possess several traits that are absent from individual yeasts. These include the ability to synchronize colony population development and adapt its metabolism to different environmental changes, such as nutrient depletion. This, together with cell diversification to cell variants with distinct metabolic and other properties, contributes to the main goal of the colony population: to achieve longevity. In this respect, a benefit to individual cells is subordinated to the benefit to the whole population, exhibiting a kind of altruistic behaviour. For example, some colony cells located at particular positions undergo regulated cell dying and provide components to other cells located in more propitious areas. The enhancement of techniques that enable the in vivo investigation of three-dimensional spatiotemporal colony development can lead to new discoveries on metabolic differentiation and regulation in the near future" . "0300-5127" . . "Biochemical Society Transactions" . . "1"^^ . "39" . .