"8"^^ . "Lincomycin derivatives are produced by biotechnological cultivation of Streptomyces lincolnensis ATCC 25466 with at least one gene of the 4-L-propylproline biosynthesis coding cluster inactivated. A substitute of the component whose synthesis is blocked by inactivation is added to the medium. In this way new, biologically active lincomycin derivatives are produced biosynthetically"@en . . . "Lincomycin; Streptomyces lincolnensis ATCC 25466"@en . "Kamen\u00EDk, Zden\u011Bk" . . . . "Ulanov\u00E1, Dana" . "P(2B08064), P(IAA500200810), Z(AV0Z50200510)" . . . . . "RIV/61388971:_____/10:00373076!RIV12-AV0-61388971" . . "2010-12-02+01:00"^^ . "300512" . "302256" . "Prague" . . "Mikrobiologick\u00FD \u00FAstav AV \u010CR, v.v.i" . "Sp\u00ED\u017Eek, Jaroslav" . . . . "Deriv\u00E1ty linkomycinu jsou p\u0159ipravov\u00E1ny biotechnologickou kultivac\u00ED Streptomyces lincolnensis ATCC 25466, kter\u00FD m\u00E1 inaktivovan\u00FD alespo\u0148 jeden gen ze sluku lmb k\u00F3duj\u00EDc\u00ED biosynt\u00E9zu 4-L-propylprolinu. Do kultiva\u010Dn\u00EDho m\u00E9dia je dod\u00E1v\u00E1na n\u00E1hrada za slo\u017Eku, jej\u00ED\u017E synt\u00E9za je inaktivac\u00ED zablokov\u00E1na. Biosynt\u00E9zou tak vznikaj\u00ED nov\u00E9, biologicky \u00FA\u010Dinn\u00E9 deriv\u00E1ty linkomycinu"@cs . "Smutn\u00E1, Yvona" . "Procedure for biotechnological production of lincomycin derivatives and its uses"@en . . . . "Deriv\u00E1ty linkomycinu jsou p\u0159ipravov\u00E1ny biotechnologickou kultivac\u00ED Streptomyces lincolnensis ATCC 25466, kter\u00FD m\u00E1 inaktivovan\u00FD alespo\u0148 jeden gen ze sluku lmb k\u00F3duj\u00EDc\u00ED biosynt\u00E9zu 4-L-propylprolinu. Do kultiva\u010Dn\u00EDho m\u00E9dia je dod\u00E1v\u00E1na n\u00E1hrada za slo\u017Eku, jej\u00ED\u017E synt\u00E9za je inaktivac\u00ED zablokov\u00E1na. Biosynt\u00E9zou tak vznikaj\u00ED nov\u00E9, biologicky \u00FA\u010Dinn\u00E9 deriv\u00E1ty linkomycinu" . . "RIV/61388971:_____/10:00373076" . "Zp\u016Fsob biotechnologick\u00E9 p\u0159\u00EDpravy deriv\u00E1t\u016F linkomycinu"@cs . "Zp\u016Fsob biotechnologick\u00E9 p\u0159\u00EDpravy deriv\u00E1t\u016F linkomycinu" . . . "Zp\u016Fsob biotechnologick\u00E9 p\u0159\u00EDpravy deriv\u00E1t\u016F linkomycinu" . "Novotn\u00E1, Jitka" . . "[8E64F2B22E3B]" . . "Ga\u017E\u00E1k, Radek" . "Zp\u016Fsob biotechnologick\u00E9 p\u0159\u00EDpravy deriv\u00E1t\u016F linkomycinu"@cs . "Janata, Ji\u0159\u00ED" . . . . "\u00DA\u0159ad pr\u016Fmyslov\u00E9ho vlastnictv\u00ED" . "Procedure for biotechnological production of lincomycin derivatives and its uses"@en . . . "Kopeck\u00FD, Jan" . "8"^^ . . . .