. . "Kov\u00E1\u010D, M." . . "Proteomick\u00E1 anal\u00FDza solubiln\u00EDch protein\u016F d\u016Fle\u017Eit\u00FDch u d\u011Btsk\u00E9 leukemie" . "16" . . "RIV/61388971:_____/10:00356982" . . "Proteomick\u00E1 anal\u00FDza solubiln\u00EDch protein\u016F d\u016Fle\u017Eit\u00FDch u d\u011Btsk\u00E9 leukemie"@cs . "3"^^ . "Proteomick\u00E1 anal\u00FDza solubiln\u00EDch protein\u016F d\u016Fle\u017Eit\u00FDch u d\u011Btsk\u00E9 leukemie"@cs . "4" . . . "[B1A1DFD0C3E5]" . . . . "Sborn\u00EDk abstrakt" . "Proteomic analysis of soluble proteins important in pediatric acute lymphoblastic leukemia"@en . "Proteomic analysis of soluble proteins important in pediatric acute lymphoblastic leukemia"@en . "Pelkov\u00E1, V." . "P(NR9531), Z(AV0Z50200510)" . "Mejst\u0159\u00EDkov\u00E1, E." . "Proteomick\u00E1 anal\u00FDza solubiln\u00EDch protein\u016F d\u016Fle\u017Eit\u00FDch u d\u011Btsk\u00E9 leukemie" . . "V\u00E1\u0161kov\u00E1, M." . "N\u011Bkter\u00E9 klinick\u00E9 symptomy u akutn\u00ED leukemie mohou vznikat v d\u016Fsledku p\u016Fsoben\u00ED solubiln\u00EDch faktor\u016F secernovan\u00FDch leukemick\u00FDmi bu\u0148kami do mikroprost\u0159ed\u00ED kostn\u00ED d\u0159en\u011B. Na druh\u00E9 stran\u011B jsou leukemick\u00E9 bu\u0148ky \u010Dasto z\u00E1visl\u00E9 ma mikroprost\u0159ed\u00ED hostitele, tak\u017Ee v\u011Bt\u0161ina leukemick\u00FDch bun\u011Bk podlehne apopt\u00F3ze b\u011Bhem prvn\u00EDch dn\u016F v in vitro podm\u00EDnk\u00E1ch" . "-" . "acute lymphoblastic leukemia; protein array; protein"@en . "CZ - \u010Cesk\u00E1 republika" . . "5"^^ . . "Petr\u00E1\u010Dkov\u00E1, Denisa" . "10"^^ . "Kalina, T." . "283077" . "Bezou\u0161kov\u00E1, Silvia" . . "Weiser, Jaroslav" . "N\u011Bkter\u00E9 klinick\u00E9 symptomy u akutn\u00ED leukemie mohou vznikat v d\u016Fsledku p\u016Fsoben\u00ED solubiln\u00EDch faktor\u016F secernovan\u00FDch leukemick\u00FDmi bu\u0148kami do mikroprost\u0159ed\u00ED kostn\u00ED d\u0159en\u011B. Na druh\u00E9 stran\u011B jsou leukemick\u00E9 bu\u0148ky \u010Dasto z\u00E1visl\u00E9 ma mikroprost\u0159ed\u00ED hostitele, tak\u017Ee v\u011Bt\u0161ina leukemick\u00FDch bun\u011Bk podlehne apopt\u00F3ze b\u011Bhem prvn\u00EDch dn\u016F v in vitro podm\u00EDnk\u00E1ch"@cs . . "In acute leukemia (AL), several clinical symptoms may be caused by soluble factors secreted by AL cells into the bonemarrow (BM) microenvironment. On the other hand, AL cells are often dependent on the microenvironment of the host, with most AL cells dying during first days after transferred to in vitro. This support of leukemic cells may be mediated by soluble factors as well. Attention is logically focused on malignant cells and the composition of soluble factors may be unjustly omitted. We aimed at identifying proteins in BM plasma of children with lymphoblastic AL(ALL), which may be responsible forALLaggressiveness or for microenvironment-mediated survival of ALLcells"@en . . . "1213-5763" . "Star\u00FD, J." . "RIV/61388971:_____/10:00356982!RIV11-AV0-61388971" . . "Hru\u0161\u00E1k, O." . .