"134" . "DE - Spolkov\u00E1 republika N\u011Bmecko" . "Molecular mass spectrometry imaging in biomedical and life science research"@en . . "This review describes the current state of mass spectrometry imaging (MSI) in life sciences. A brief overview of mass spectrometry principles is presented followed by a thorough introduction to the MSI workflows, principles and areas of application. Three major desorptionionization techniques used in MSI, namely, secondary ion mass spectrometry (SIMS), matrix-assisted laser desorption ionization (MALDI), and desorption electrospray ionization (DESI) are described, and biomedical and life science imaging applications of each ionization technique are reviewed. A separate section is devoted to data handling and current challenges and future perspectives are briefly discussed at the end" . "Molecular mass spectrometry imaging in biomedical and life science research" . . "P(GPP206/10/P018), P(LC545), Z(AV0Z50200510)" . . "P\u00F3l, Jaroslav" . "21"^^ . "Mass spectrometry; Chemical imaging; Molecular imaging"@en . "Havl\u00ED\u010Dek, Vladim\u00EDr" . . . . . . . "[B60CD20FE1CE]" . . "Molecular mass spectrometry imaging in biomedical and life science research" . "Strohalm, Martin" . . "Voln\u00FD, Michael" . "4"^^ . "000284070700001" . "Histochemistry and Cell Biology" . "4"^^ . . . . . "272388" . "Molecular mass spectrometry imaging in biomedical and life science research"@en . "This review describes the current state of mass spectrometry imaging (MSI) in life sciences. A brief overview of mass spectrometry principles is presented followed by a thorough introduction to the MSI workflows, principles and areas of application. Three major desorptionionization techniques used in MSI, namely, secondary ion mass spectrometry (SIMS), matrix-assisted laser desorption ionization (MALDI), and desorption electrospray ionization (DESI) are described, and biomedical and life science imaging applications of each ionization technique are reviewed. A separate section is devoted to data handling and current challenges and future perspectives are briefly discussed at the end"@en . . "RIV/61388971:_____/10:00354266" . . . . "RIV/61388971:_____/10:00354266!RIV11-GA0-61388971" . "0948-6143" . "5" . . .