. "Lemr, Karel" . . . "Magnesium interference and different efficiencies of diastereoisomeric cluster formation in phenylalanine enantiomeric discrimination by the kinetic method"@en . "RIV/61388971:_____/09:00328370!RIV10-MSM-61388971" . . "Bedn\u00E1\u0159, P." . "280" . "1-3" . "Havl\u00ED\u010Dek, Vladim\u00EDr" . "P(GA203/07/0765), P(LC07017), Z(AV0Z50200510), Z(MSM6198959216)" . "2"^^ . . . . "The kinetic method has been applied for determination of d-Phe/l-Phe enantiomeric ratio. Discrimination of enantiomers was inferred from product ion mass spectra of trimeric cluster ions containing the analyte (l,d-Phe), Cu2 as a central metal and l-Trp as a chiral reference ligand. Unsatisfactory quantitative results achieved on an ion trapwere rationalized by high-resolution mass spectrometry. The formation of Mg2-containing cluster isobaric to trimeric cluster [Cu(l-Trp)2Phe] was observed. Interference like this was identified as a possible reason for deterioration of quantitative low-resolution mass spectrometric analyses of real-world samples based on the kinetic method. Cation-exchangerwas used for easy removal of magnesium from a sample and improvement of quantitation. Chiral dependence of formation of the Cu2 containing trimeric clusterwas also observed. Heterochiral diastereoisomeric ions were created less effectively" . . "Magnesium interference and different efficiencies of diastereoisomeric cluster formation in phenylalanine enantiomeric discrimination by the kinetic method" . "RIV/61388971:_____/09:00328370" . "4"^^ . . "International Journal of Mass Spectrometry" . "1387-3806" . "Ranc, V." . "324332" . "000263195500034" . "The kinetic method has been applied for determination of d-Phe/l-Phe enantiomeric ratio. Discrimination of enantiomers was inferred from product ion mass spectra of trimeric cluster ions containing the analyte (l,d-Phe), Cu2 as a central metal and l-Trp as a chiral reference ligand. Unsatisfactory quantitative results achieved on an ion trapwere rationalized by high-resolution mass spectrometry. The formation of Mg2-containing cluster isobaric to trimeric cluster [Cu(l-Trp)2Phe] was observed. Interference like this was identified as a possible reason for deterioration of quantitative low-resolution mass spectrometric analyses of real-world samples based on the kinetic method. Cation-exchangerwas used for easy removal of magnesium from a sample and improvement of quantitation. Chiral dependence of formation of the Cu2 containing trimeric clusterwas also observed. Heterochiral diastereoisomeric ions were created less effectively"@en . . . . . . . "Magnesium interference and different efficiencies of diastereoisomeric cluster formation in phenylalanine enantiomeric discrimination by the kinetic method" . "5"^^ . . . "[4BB9B8F0E622]" . "Magnesium interference and different efficiencies of diastereoisomeric cluster formation in phenylalanine enantiomeric discrimination by the kinetic method"@en . . "enantiomeric dicrimination; kinetic method; mass spectrometry"@en . "NL - Nizozemsko" . . .