. "11"^^ . . "37" . "P(GA203/09/0317), P(LC512), Z(AV0Z40550506)" . "2"^^ . "Nucleic Acids Research" . . "functionalized DNA; restriction endonucleases; DNA polymerase; modified adenosines"@en . "A set of base-modified 2'-deoxyadenosine derivatives was incorporated to diverse DNA sequences by primer extension and the influence of the modification on cleavage by diverse restriction endonucleases was studied. While 8-substituted adenine derivatives were well tolerated by the enzymes, the presence of 7-substituted 7-deazaadenine in the recognition sequence resulted in blocking of cleavage by some enzymes depending on the nature and size of the 7-substituent. The results are useful both for protection of some sequences from cleavage and for manipulation of functionalized DNA by restriction cleavage."@en . "2"^^ . "Hocek, Michal" . "RIV/61388963:_____/09:00334373!RIV10-MSM-61388963" . . . . "Cleavage of adenine-modified functionalized DNA by type II restriction endonucleases" . . . "000272935000032" . . "A set of base-modified 2'-deoxyadenosine derivatives was incorporated to diverse DNA sequences by primer extension and the influence of the modification on cleavage by diverse restriction endonucleases was studied. While 8-substituted adenine derivatives were well tolerated by the enzymes, the presence of 7-substituted 7-deazaadenine in the recognition sequence resulted in blocking of cleavage by some enzymes depending on the nature and size of the 7-substituent. The results are useful both for protection of some sequences from cleavage and for manipulation of functionalized DNA by restriction cleavage." . . "GB - Spojen\u00E9 kr\u00E1lovstv\u00ED Velk\u00E9 Brit\u00E1nie a Severn\u00EDho Irska" . . "Cleavage of adenine-modified functionalized DNA by type II restriction endonucleases"@en . . "307256" . . . "[5468F5B47D31]" . "RIV/61388963:_____/09:00334373" . . "Cleavage of adenine-modified functionalized DNA by type II restriction endonucleases" . "22" . . "0305-1048" . . "Cleavage of adenine-modified functionalized DNA by type II restriction endonucleases"@en . . . "Mac\u00ED\u010Dkov\u00E1-Cahov\u00E1, Hana" . .