"7"^^ . . "P(1M0508), P(1QS400550501), Z(AV0Z40550506)" . "Use of Pd-catalyzed Suzuki-Miyaura coupling reaction in the rapid synthesis of 5-aryl-6-(phosphonomethoxy)uracils and evaluation of their inhibitory effect towards human thymidine phosphorylase"@en . "000270345900005" . . "A number of new 5-aryl substituted pyrimidine acyclic nucleoside phosphonates were synthesized and tested for their ability to inhibit human TP. Their rapid synthesis using Pd-catalyzed Suzuki-Miyaura coupling reactions of various arylboronic acids with 5-bromo-4-(phosphonomethoxy)-2,6-dibutoxypyrimidine was succesfully applied. For a series of 5-aryl-6-phosphonomethoxyuracils, an increased inhibitory effect was determined. This effect is supported by the results found for 4-fluorophenyl (KidThd = 4.89 0.62) and 3-nitrophenyl (KidThd = 3.98 0.46) substituents." . . "[73DAFEA2FF3D]" . "Pohl, Radek" . . . "Use of Pd-catalyzed Suzuki-Miyaura coupling reaction in the rapid synthesis of 5-aryl-6-(phosphonomethoxy)uracils and evaluation of their inhibitory effect towards human thymidine phosphorylase" . "A number of new 5-aryl substituted pyrimidine acyclic nucleoside phosphonates were synthesized and tested for their ability to inhibit human TP. Their rapid synthesis using Pd-catalyzed Suzuki-Miyaura coupling reactions of various arylboronic acids with 5-bromo-4-(phosphonomethoxy)-2,6-dibutoxypyrimidine was succesfully applied. For a series of 5-aryl-6-phosphonomethoxyuracils, an increased inhibitory effect was determined. This effect is supported by the results found for 4-fluorophenyl (KidThd = 4.89 0.62) and 3-nitrophenyl (KidThd = 3.98 0.46) substituents."@en . "Tetrahedron" . "65" . . "GB - Spojen\u00E9 kr\u00E1lovstv\u00ED Velk\u00E9 Brit\u00E1nie a Severn\u00EDho Irska" . "Horsk\u00E1, Kv\u011Btoslava" . . "0040-4020" . . . . "41" . "RIV/61388963:_____/09:00330906!RIV10-MSM-61388963" . "Use of Pd-catalyzed Suzuki-Miyaura coupling reaction in the rapid synthesis of 5-aryl-6-(phosphonomethoxy)uracils and evaluation of their inhibitory effect towards human thymidine phosphorylase" . . "347913" . . . "RIV/61388963:_____/09:00330906" . . "4"^^ . . "Use of Pd-catalyzed Suzuki-Miyaura coupling reaction in the rapid synthesis of 5-aryl-6-(phosphonomethoxy)uracils and evaluation of their inhibitory effect towards human thymidine phosphorylase"@en . . . "4"^^ . . "acyclic nucleoside phosphonates; Suzuki-Miyaura reaction; thymidine phosphorylase; human thymidine phosphorylase"@en . . . "Pomeisl, Karel" . "Hol\u00FD, Anton\u00EDn" . . .