. . "Nucleosides and nucleotides containing 8-aza-7,9-dideazaxanthine" . "The described preparation of 8-aza-7,9-dideazaxanthine from 1,3-dibenzyluracil and TosMIC was improved by using AlCl3 for final debenzylation. Treatment of 6-dibromomethyl- 5-formyluracil with benzyl-, 4-methoxybenzyl-, and 1-adamantylamine gave the corresponding 8-alkyl-8-aza-7,9-dideazaxanthines. N1- and N8-(8-phosphonooctyl)-8-aza-7,9-dideazaxanthines were prepared and found as inhibitors of thymidine phosphorylase (V79 cells, human placenta, Escherichia coli). IC50 values ranged at 3\u201327 .mu.M." . "\u010Cesk\u00FD Krumlov" . "Nucleosides and nucleotides containing 8-aza-7,9-dideazaxanthine" . . . "383413" . "Praha" . "000257885700102" . "Nucleosides and nucleotides containing 8-aza-7,9-dideazaxanthine"@en . . "Otmar, Miroslav" . . . "978-80-86241-29-6" . . . "5"^^ . . . "Ma\u0159\u00E1k, David" . . "Votruba, Ivan" . . . . "5"^^ . . "[4B7E0AA58DCB]" . "P(1M0508), P(1QS400550501), Z(AV0Z40550506)" . "8-Aza-7,9-dideazaxanthin byl p\u0159ipraven pomoc\u00ED TosMIC a 1,3-dibenzyluracilu. Postup byl vylep\u0161en u\u017Eit\u00EDm AlCl3 pro fin\u00E1ln\u00ED debenzylaci. 8-Alkyl-8-aza-7,9-dideazaxanthiny byly p\u0159ipraveny reakc\u00ED 6-dibromomethyl-5-formyluracilu s benzyl-, 4 methoxybenzyl-, a 1 adamantylaminem. Bylo zji\u0161t\u011Bno \u017Ee N1- a N8-(8-fosfonooktyl)-8-aza-7,9-dideazaxanthin jsou u\u010Dinn\u00FDmi inhibitory thymidin fosforylasy (V79 bu\u0148ky, lidsk\u00E1 placenta, Escherichia coli). Hodnoty IC50 3\u201327 .mu.M."@cs . "RIV/61388963:_____/08:00310039" . . . . "Nukleosidy a nukleotidy obsahuj\u00EDc\u00ED 8-aza-7,9-dideazaxanthin"@cs . . "2008-06-08+02:00"^^ . . . . "Chemistry of Nucleic Acid Components" . "Dra\u010D\u00EDnsk\u00FD, Martin" . "The described preparation of 8-aza-7,9-dideazaxanthine from 1,3-dibenzyluracil and TosMIC was improved by using AlCl3 for final debenzylation. Treatment of 6-dibromomethyl- 5-formyluracil with benzyl-, 4-methoxybenzyl-, and 1-adamantylamine gave the corresponding 8-alkyl-8-aza-7,9-dideazaxanthines. N1- and N8-(8-phosphonooctyl)-8-aza-7,9-dideazaxanthines were prepared and found as inhibitors of thymidine phosphorylase (V79 cells, human placenta, Escherichia coli). IC50 values ranged at 3\u201327 .mu.M."@en . "RIV/61388963:_____/08:00310039!RIV09-AV0-61388963" . . "Nukleosidy a nukleotidy obsahuj\u00EDc\u00ED 8-aza-7,9-dideazaxanthin"@cs . "8-Aza-7,9-dideaza; xanthine; thymidine phosporylase; debenzylation"@en . "3"^^ . . "Institute of Organic Chemistry and Biochemistry ASCR" . "Hol\u00FD, Anton\u00EDn" . "Nucleosides and nucleotides containing 8-aza-7,9-dideazaxanthine"@en .