"US - Spojen\u00E9 st\u00E1ty americk\u00E9" . "[2CCDA5B8BBA0]" . "RIV/61388963:_____/05:00021197" . . "2"^^ . "9"^^ . "The chemical characteristics of the polar parts of phospholipids were investigated by using infrared (IR) spectroscopy and theoretical calculations with water as a probe molecule. The main process appearing upon progressive hydration is unfolding of methylphosphocholine (MePC) molecules that are closely packed in isolated state. The stepwise disruption of the intramolecular hydrogen bonds stabilizing the original packed structure of MePC is connected in substantial changes in vibrational properties of MePC. The mechanism of hydration-driven conformational changes occurring in MePC could be transferred to other zwitterions with relevant internal C-H...O hydrogen bonds." . . . "523938" . . "Hydration-induced changes of structure and vibrational frequencies of methylphosphocholine studied as a model of biomembrane lipids" . "-" . "Hydration-induced changes of structure and vibrational frequencies of methylphosphocholine studied as a model of biomembrane lipids"@en . . . "Hobza, Pavel" . "15126;15134" . "Charakteristiky pol\u00E1rn\u00EDch \u010D\u00E1st\u00ED fosfolipid\u016F a jejich interakce s vodou byly studov\u00E1ny pomoc\u00ED infra\u010Derven\u00E9 spektroskopie a teoretick\u00FDch v\u00FDpo\u010Dt\u016F. Hlavn\u00ED proces, k n\u011Bmu\u017E doch\u00E1z\u00ED p\u0159i postupn\u00E9 hydrataci, je konforma\u010Dn\u00ED zm\u011Bna molekuly metylfosfocholinu z t\u011Bsn\u011B sbalen\u00E9, kter\u00E1 je v isolovan\u00E9m stavu, na rozbalenou d\u00EDky poru\u0161en\u00ED intramolekulov\u00FDch vod\u00EDkov\u00FDch vazeb. Tato konforma\u010Dn\u00ED zm\u011Bna je doprov\u00E1zena dob\u0159e pozorovateln\u00FDmi zm\u011Bnami ve vibra\u010Dn\u00EDch charakteristik\u00E1ch. Nazna\u010Den\u00FD mechanismus konforma\u010Dn\u00EDch zm\u011Bn indukovan\u00FDch hydratac\u00ED je pravd\u011Bpodobn\u011B obecn\u011B platn\u00FD pro v\u0161echny zwitterionty s relevatn\u00EDmi intramolekulov\u00FDmi vod\u00EDkov\u00FDmi vazbami."@cs . "Hydration-induced changes of structure and vibrational frequencies of methylphosphocholine studied as a model of biomembrane lipids" . "Bohl, M." . "109" . . "Gauger, D. R." . "Pohle, W." . . "Hydratac\u00ED indukovan\u00E9 zm\u011Bny struktury a vibra\u010Dn\u00EDch vlastnost\u00ED methylfosfocholinu, model membr\u00E1nov\u00E9ho lipidu"@cs . "hydrogen bonding; zwitterions; vibrational properties of hydrogen bonded complexes"@en . . "Hydration-induced changes of structure and vibrational frequencies of methylphosphocholine studied as a model of biomembrane lipids"@en . . . . "1520-6106" . . "P(GA203/05/0009), P(LC512), Z(AV0Z40550506)" . . "Mr\u00E1zkov\u00E1, Eva" . "5"^^ . . . "Journal of Physical Chemistry B" . . "The chemical characteristics of the polar parts of phospholipids were investigated by using infrared (IR) spectroscopy and theoretical calculations with water as a probe molecule. The main process appearing upon progressive hydration is unfolding of methylphosphocholine (MePC) molecules that are closely packed in isolated state. The stepwise disruption of the intramolecular hydrogen bonds stabilizing the original packed structure of MePC is connected in substantial changes in vibrational properties of MePC. The mechanism of hydration-driven conformational changes occurring in MePC could be transferred to other zwitterions with relevant internal C-H...O hydrogen bonds."@en . . . "Hydratac\u00ED indukovan\u00E9 zm\u011Bny struktury a vibra\u010Dn\u00EDch vlastnost\u00ED methylfosfocholinu, model membr\u00E1nov\u00E9ho lipidu"@cs . "RIV/61388963:_____/05:00021197!RIV06-MSM-61388963" .