"1" . "European Journal of Mass Spectrometry" . "\u0160pan\u011Bl, Patrik" . . "selected ion flow tube mass spectroscopy (SIFT-MS); breath analysis; breath metabolities; flowing afterglow mass spectrometry (FA-MS)"@en . "RIV/61388955:_____/07:00308433!RIV08-AV0-61388955" . . "Selected ion flow tube mass spectrometry for on-line trace gas analysis in biology and medicine" . "P(GA202/06/0776), Z(AV0Z40400503)" . "2"^^ . "RIV/61388955:_____/07:00308433" . . "Selected ion flow tube mass spectrometry, (SIFT-MS), is a technique for simultaneous real-time quantification of several trace gases in air and exhaled breath. It relies on chemical ionization of the trace gas molecules in air/breath samples introduced into helium carrier gas, using H3O+, NO+ and O2+ reagent (precursor ions). Reactions between the precursor ions and the trace gas molecules proceed for an accurately defined time, the precursor and product ions being detected and counted by a downstream mass spectrometer. Absolute concentrations of trace gases in single breath exhalation can be determined by SIFT-MS down to parts-per-billion (ppb) levels, obviating sample collection into bags or onto traps. Calibration using chemical standards is not required, as the concentrations are calculated using the known reaction rate constants and measured flow rates and pressures."@en . "1"^^ . . . "Hmotnostn\u00ED spektrometrie v proudov\u00E9 trubici s vybran\u00FDmi ionty pro okam\u017Eitou stopovou anal\u00FDzu v biologii a medic\u00EDn\u011B"@cs . . . . "6"^^ . . "449243" . . "GB - Spojen\u00E9 kr\u00E1lovstv\u00ED Velk\u00E9 Brit\u00E1nie a Severn\u00EDho Irska" . . . "1469-0667" . "77;82" . "13" . . "[ABD8D40927EF]" . . . "Selected ion flow tube mass spectrometry, (SIFT-MS), is a technique for simultaneous real-time quantification of several trace gases in air and exhaled breath. It relies on chemical ionization of the trace gas molecules in air/breath samples introduced into helium carrier gas, using H3O+, NO+ and O2+ reagent (precursor ions). Reactions between the precursor ions and the trace gas molecules proceed for an accurately defined time, the precursor and product ions being detected and counted by a downstream mass spectrometer. Absolute concentrations of trace gases in single breath exhalation can be determined by SIFT-MS down to parts-per-billion (ppb) levels, obviating sample collection into bags or onto traps. Calibration using chemical standards is not required, as the concentrations are calculated using the known reaction rate constants and measured flow rates and pressures." . . "Hmotnostn\u00ED spektrometrie v proudov\u00E9 trubici s vybran\u00FDmi ionty pro okam\u017Eitou stopovou anal\u00FDzu v biologii a medic\u00EDn\u011B"@cs . "Selected ion flow tube mass spectrometry for on-line trace gas analysis in biology and medicine"@en . "Selected ion flow tube mass spectrometry for on-line trace gas analysis in biology and medicine"@en . . . "Hmotnostn\u00ED spektrometrie v proudov\u00E9 trubici s vybran\u00FDmi ionty SIFT-MS p\u0159edstavuje metodu pro sou\u010Dasnou anal\u00FDzu n\u011Bkolika stopov\u00FDch plyn\u016F v re\u00E1ln\u00E9m \u010Dase. Pou\u017E\u00EDv\u00E1 se pro m\u011B\u0159en\u00ED koncentrac\u00ED ve vzduchu a lidsk\u00E9m dechu. Metoda je zalo\u017Eena na chemick\u00E9 ionisaci molekul stopov\u00FDch l\u00E1tek p\u0159\u00EDtomn\u00FDch ve vzorku vzduchu nebo dechu pomoc\u00ED iont\u016F H3O+, NO+ a O2+. Tyto reagenty neboli prekurzorov\u00E9 ionty reaguj\u00ED b\u011Bhem p\u0159esn\u011B definovan\u00E9 doby a produkty t\u011Bchto reakc\u00ED jsou separov\u00E1ny a kvantifikov\u00E1ny hmotnostn\u00EDm spektrometrem um\u00EDst\u011Bn\u00FDm na konci proudov\u00E9 trubice. Absolutn\u00ED koncentrace stopov\u00FDch l\u00E1tek mohou b\u00FDt m\u011B\u0159eny od stupn\u011B na\u0159ed\u011Bn\u00ED jedna ku miliard\u011B i v jedin\u00E9m v\u00FDdechu. Koncentrace l\u00E1tek jsou vypo\u010Dteny ze zn\u00E1m\u00FDch rychlostn\u00EDch konstant a m\u011B\u0159en\u00FDch pr\u016Ftok\u016F nosn\u00E9ho plynu helia a p\u0159iv\u00E1d\u011Bn\u00E9ho vzorku. Uvedeny jsou p\u0159\u00EDklady pou\u017Eit\u00ED SIFT-MS pro neinvazivn\u00ED anal\u00FDzu dechu pro v\u00FDzkum fyziologick\u00FDch proces\u016F u lid\u00ED a zv\u00ED\u0159at. Klinickou diagnostiku, monitorov\u00E1n\u00ED terapie a dal\u0161\u00ED oblasti."@cs . "Smith, D." . "Selected ion flow tube mass spectrometry for on-line trace gas analysis in biology and medicine" .