"Constant Current Chronopotentiometric Stripping Analysis using adsorptive accumulation and negative current (AdSCP) was applied as an alternative for the study of metal complexation of glutathione (GSH) or .gamma.-Glu-Cys)2-Gly (PC2) with zinc ions on hanging mercury drop electrode. The behavior of the formed Zn-complexes was studied using voltammetric and chronopotentiometric methods. A multivariate curve resolution method by alternating least-squares (MCR-ALS) applied to DP voltammetric and chronopotentiometric measurements of Zn-PC2 system made possible the formulation of a complexation model. Moreover, the use of small currents in AdSCP allows one to obtain acceptable sensitivities and signal separation at very low concentrations, which is important in peptide studies under conditions similar to these of natural media."@en . "0022-0728" . "1" . "Arino, C." . "Constant Current Chronopotentiometric Stripping Analysis using adsorptive accumulation and negative current (AdSCP) was applied as an alternative for the study of metal complexation of glutathione (GSH) or .gamma.-Glu-Cys)2-Gly (PC2) with zinc ions on hanging mercury drop electrode. The behavior of the formed Zn-complexes was studied using voltammetric and chronopotentiometric methods. A multivariate curve resolution method by alternating least-squares (MCR-ALS) applied to DP voltammetric and chronopotentiometric measurements of Zn-PC2 system made possible the formulation of a complexation model. Moreover, the use of small currents in AdSCP allows one to obtain acceptable sensitivities and signal separation at very low concentrations, which is important in peptide studies under conditions similar to these of natural media." . "Adsorptive accumulation in constant current stripping chronopotentiometry as an alternative for the electrochemical study of metal complexation by thiol\u2013containing peptides"@en . "Journal of the Electroanalytical Chemistry and Journal of Electroanalytical Chemistry and Interfacial Electrochemistry" . "CH - \u0160v\u00FDcarsk\u00E1 konfederace" . "Diaz-Cruz, J. M." . "464215" . "Adsorptivn\u00ED akumulace v rozpou\u0161t\u011Bc\u00ED chronopotenciometrii s konstantn\u00EDm proudem jako alternativa pro elektrochemick\u00E9 studium komplexace kov\u016F peptidy s thiolovou skupinou"@cs . "105;117" . . "Adsorptive accumulation in constant current stripping chronopotentiometry as an alternative for the electrochemical study of metal complexation by thiol\u2013containing peptides" . "Adsorptivn\u00ED akumulace v rozpou\u0161t\u011Bc\u00ED chronopotenciometrii s konstantn\u00EDm proudem jako alternativa pro elektrochemick\u00E9 studium komplexace kov\u016F peptidy s thiolovou skupinou"@cs . . "591" . . . . "13"^^ . . "Adsorptive accumulation in constant current stripping chronopotentiometry as an alternative for the electrochemical study of metal complexation by thiol\u2013containing peptides" . "P(OC D21.002), Z(AV0Z40400503)" . . "RIV/61388955:_____/06:00039315" . "4"^^ . "stripping chronopotentiometry; adsorptive accumulation; phytochelatins; glutathione"@en . . . . "1"^^ . . . . . "[6E19D22710C2]" . "Adsorptive accumulation in constant current stripping chronopotentiometry as an alternative for the electrochemical study of metal complexation by thiol\u2013containing peptides"@en . . . "\u0160est\u00E1kov\u00E1, Ivana" . . "RIV/61388955:_____/06:00039315!RIV07-AV0-61388955" . . "Serrano, N." . "Chronopotenciometrick\u00E1 rozpou\u0161t\u011Bc\u00ED anal\u00FDza na vis\u00EDc\u00ED rtu\u0165ov\u00E9 kapkov\u00E9 elektrod\u011B, s aplikac\u00ED adsorptivn\u00ED akumulace a z\u00E1porn\u00E9ho rozpou\u0161t\u011Bc\u00EDho proudu (AdSCP), byla pou\u017Eita pro studium komplexace glutathionu (GSH) a .gamma.-Glu-Cys)2-Gly (PC2) s ionty zinku. Chov\u00E1n\u00ED vznikl\u00FDch Zn-komplex\u016F bylo studov\u00E1no pomoc\u00ED voltametrick\u00FDch a chronopotenciometrick\u00FDch metod. Metoda multivaria\u010Dn\u00EDho rozli\u0161en\u00ED k\u0159ivek a alternuj\u00EDc\u00EDch nejmen\u0161\u00EDch \u010Dtverc\u016F (MCR-ALS) byla aplikov\u00E1na na m\u011B\u0159en\u00ED DP voltametrie a chronopotenciometrie, co\u017E umo\u017Enilo navr\u017Een\u00ED komplexa\u010Dn\u00EDho modelu pro Zn- PC2 syst\u00E9m. Krom\u011B toho, pou\u017Eit\u00ED mal\u00FDch proud\u016F v AdSCP znamen\u00E1 dosa\u017Een\u00ED p\u0159ijateln\u00E9 citlivosti a rozli\u0161en\u00ED sign\u00E1l\u016F p\u0159i velmi mal\u00FDch koncentrac\u00EDch, co\u017E je v\u00FDznamn\u00E9 pro studium peptid\u016F za podm\u00EDnek obdobn\u00FDch p\u0159\u00EDrodn\u00EDmu prost\u0159ed\u00ED."@cs .